Gipuzkoa
Al maig de 2006, es va posar en marxa a Guipúscoa el projecte “INfància i Medi Ambient (INMA)” per tal d’avaluar el paper dels contaminants ambientals presents en l’aire, en l’aigua i en la dieta en el creixement i desenvolupament dels infants. La incorporació de les mares a la cohort es va fer coincidir amb la primera ecografia de control de l’embaràs. Es van recollir mostres biològiques (sang, orina, cabell, placenta, etc.) i els van fer omplir diversos qüestionaris (general, dieta, laboral, ambiental, etc.). Després es va fer la valoració dels contaminants presents en l’aire i en l’aigua de consum, així com una estimació dels contaminants que aportava la dieta.
L’àmbit geogràfic d’estudi ve definit per la població de referència de l’Hospital Zumarraga, que inclou els municipis de Goierri i de l’Alt i Mitjà Urola. Aquest entorn es va seleccionar per les característiques del servei de l’Hospital i l’atenció primària implicats, així com per les característiques ambientals: presència massiva d’indústries siderometal·lúrgiques, alta densitat de trànsit, els nivells baixos de productes derivats de la desinfecció en l’aigua de consum i una dieta rica en peix, units a un cert grau d’hipotiroïdisme en les dones embarassades.
Des de llavors, s’ha fet el seguiment de 640 dones en el primer i tercer trimestre de l’embaràs. Actualment, s’està fent el seguiment de 623 nens en aspectes de creixement i de desenvolupament neuroconductual.
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Finançadors de la cohort INMA-Gipuzkoa:
This study was funded by grants from Instituto de Salud Carlos III (FIS-PI06/0867, FIS-PI09/00090, FIS-PI13/02187 and FIS-PI18/01142 incl. FEDER funds), CIBERESP, Department of Health of the Basque Government (2005111093, 2009111069, 2013111089 and 2015111065), and the Provincial Government of Gipuzkoa (DFG06/002, DFG08/001 and DFG15/221) and annual agreements with the municipalities of the study area (Zumarraga, Urretxu, Ordizia, Legazpi, Azkoitia y Azpeitia y Beasain).
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Entitats Col·laboradores:
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Association of Gestational Weight Gain With Adverse Maternal and Infant Outcomes
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Impact of maternal body mass index and gestational weight gain on pregnancy complications: an individual participant data meta-analysis of European, North American and Australian cohorts
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Maternal nut intake in pregnancy and child neuropsychological development up to 8 years old: a population‑based cohort study in Spain
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Effect modification of FADS2 polymorphisms on the association between breastfeedingand intelligence: results from a collaborative meta-analysis
Hartwig FP, Davies NM, Horta BL, Ahluwalia TS, Bisgaard H, Bønnelykke K, Caspi A, Moffitt TE, Poulton R, Sajjad A, Tiemeier HW, Dalmau-Bueno A, Guxens M, Bustamante M, Santa-Marina L, Parker N, Paus T, Pausova Z, Lauritzen L, Schnurr TM, Michaelsen KF, Hansen T, Oddy W, Pennell CE, Warrington NM, Davey Smith G, Victora CG. Effect modification of FADS2 polymorphisms on the association between breastfeedingand intelligence: results from a collaborative meta-analysis. Int J Epidemiol. 2019 Feb 1;48(1):45-57. PMID: 30541029
Exposure and health risks perception of extremely low frequency and radiofrequency electromagnetic fields and the effect of providing information
Gallastegi M, Jiménez-Zabala A, Molinuevo A, Aurrekoetxea JJ, Santa-Marina L, Vozmediano L, Ibarluzea J. Exposure and health risks perception of extremely low frequency and radiofrequency electromagnetic fields and the effect of providing information. Environ Res. 2019 Feb;169:501-509. PMID: 30530090
Manganese levels in newborns’ hair by maternal sociodemographic, dietary and environmental factors
Irizar A, Gil F, Lertxundi A, Martín-Domingo MC, Urbieta N, Molinuevo A, Ibarluzea J, Basterrechea M, Aurrekoetxea JJ, Jiménez-Zabala A, Santa-Marina L. Manganese levels in newborns’ hair by maternal sociodemographic, dietary and environmental factors. Environ Res. 2019 Mar;170:92-100. PMID: 30576994
High doses of folic acid in the periconceptional period and risk of low weight for gestational age at birth in a population based cohor
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Effect of employment and domestic load on fetal development and length of gestation in a birth cohort study
Arizo-Luque V, García AM, Estarlich M, Ballester F, Fernández-Tardón G, Tardón A, Guxens M, Vrijheid M, Lertxundi A, Santa-Marina L, Ronda-Pérez E. [Effect of employment and domestic load on fetal development and length of gestation in a birth cohort study]. Rev Esp Salud Publica. 2018 Aug 17;92. Spanish. PMID: 30106066
The Association of Mediterranean Diet during Pregnancy with Longitudinal Body Mass Index Trajectories and Cardiometabolic Risk in Early Childhood
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Head circumference and child ADHD symptoms and cognitive functioning: results from a large population-based cohort study
Ferrer M, García-Esteban R, Iñiguez C, Costa O, Fernández-Somoano A, Rodríguez-Delhi C, Ibarluzea J, Lertxundi A, Tonne C, Sunyer J, Julvez J. Head circumference and child ADHD symptoms and cognitive functioning: results from a large population-based cohort study. Eur Child Adolesc Psychiatry. 2019 Mar;28(3):377-388. PMID: 30027417
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