Gipuzkoa

2006ko maiatzean, “Haurtzaroa eta Ingurumena” (INMA) proiektua jarri zen martxan Gipuzkoan. Helburu nagusia zen airean, uretan eta dietan aurkitzen diren ingurumen-kutsatzaileek haurren hazkuntzan etagarapenean izan dezaketen eragina aztertzea. Emakumeak haurdunaldiko kontrolaren lehen ekografia egitean sartzen dira kohortean.Lagin biologikoak (odola, gernua, ilea, plazenta, eta abar) jasotzeaz gain, zenbait galdesorta (orokorra, dietaz, lanaz, ingurugiroaz, eta abar) betetzen dira, batetik, airean, ingurugiroan eta kontsumoko uretan aurkitzen diren kutsatzaileen balorazioa egiteko, eta, bestetik, dieta bidez jasotako kutsatzaileen estimazioa ateratzeko.

Zumarragako Ospitaleari dagokion biztanleriak definitzen du ikerketaren inguru geografikoa, hau da, Goierriko eta Urola Garaiko nahiz Urola Erdiko udalerriak. Inguru hori aukeratu zen, hain zuen, lehen mailako arreta eskaintzeagatik eta ospitaleko zerbitzuen ezaugarriengatik, eta baita ingurumen ezaugarriengatik ere: industria siderometalurgiko ugaria, zirkulazio-dentsitate altua, desinfektatzetik eratorritako produktuen maila baxua edateko uretan, arrain ugariko dieta, eta, horiekin batera, hipotiroidismo pixka bat emakume haurdunengan.

Orduz geroztik, 640 emakumeren jarraipena egin da haurdunaldiaren lehenengo eta hirugarren hilabeteetan. Gaur egun, 623 haurren jarraipena egiten ari gara hazkuntzaren eta garapen neurokonduktualaren gainean.

  • Financiadores de la cohorte INMA-Gipuzkoa:

This study was funded by grants from Instituto de Salud Carlos III (FIS-PI06/0867, FIS-PI09/00090, FIS-PI13/02187 and FIS-PI18/01142 incl. FEDER funds), CIBERESP, Department of Health of the Basque Government (2005111093, 2009111069, 2013111089 and 2015111065), and the Provincial Government of Gipuzkoa (DFG06/002, DFG08/001 and DFG15/221) and annual agreements with the municipalities of the study area (Zumarraga, Urretxu , Legazpi, Azkoitia y Azpeitia y Beasain).

  • Entidades Colaboradoras:

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318 Resultados

Neurodesarrollo -
Salud reproductiva -


Association between relative age at school and persistence of ADHD in prospective studies: an individual participant data meta-analysis

Synergy for the Influence of the Month of Birth in ADHD (SIMBA) study group. Association between relative age at school and persistence of ADHD in prospective studies: an individual participant data meta-analysis. Lancet Psychiatry. 2023 Dec;10(12):922-933. PMID: 37898142


Contaminación del aire -
Crecimiento intrauterino -


Susceptible windows of exposure to fine particulate matter and fetal growth trajectories in the Spanish INMA (INfancia y Medio Ambiente) birth cohort

Chen WJ, Rector AM, Guxens M, Iniguez C, Swartz MD, Symanski E, Ibarluzea J, Ambros A, Estarlich M, Lertxundi A, Riano-Galán I, Sunyer J, Fernandez-Somoano A, Chauhan SP, Ish J, Whitworth KW. Susceptible windows of exposure to fine particulate matter and fetal growth trajectories in the Spanish INMA (INfancia y Medio Ambiente) birth cohort. Environ Res. 2023 Jan 1;216(Pt 2):114628. PMID: 36279916


Actividad física - sedentarismo -
Contaminación del aire -
Crecimiento postnatal y Obesidad -
Desigualdades sociales -
Entorno urbano y Verdor -
Neurodesarrollo -


Social inequalities, green and blue spaces and mental health in 6-12 years old children participating in the INMA cohort

Subiza-Pérez M, García-Baquero G, Fernández-Somoano A, Riaño I, González L, Delgado-Saborit JM, Guxens M, Fossati S, Vrijheid M, Fernandes A, Ibarluzea J, Lertxundi N. Social inequalities, green and blue spaces and mental health in 6-12 years old children participating in the INMA cohort. Health Place. 2023 Sep;83:103104. PMID: 37611380


Actividad física - sedentarismo -
Contaminación del aire -
Crecimiento postnatal y Obesidad -
Desigualdades sociales -
Entorno urbano y Verdor -
Neurodesarrollo -


Residential green and blue spaces and working memory in children aged 6-12 years old. Results from the INMA cohort

Subiza-Pérez M, García-Baquero G, Fernández-Somoano A, Guxens M, González L, Tardón A, Dadvand P, Estarlich M, de Castro M, McEachan RRC, Ibarluzea J, Lertxundi N. Residential green and blue spaces and working memory in children aged 6-12 years old. Results from the INMA cohort. Health Place. 2023 Nov;84:103136. PMID: 37871446


Compuestos tóxicos no persistentes -


Optimization for the analysis of 42 per- and polyfluorinated substances in human plasma: A high-throughput method for epidemiological studies

San Román A, Abilleira E, Irizar A, Santa-Marina L, Gonzalez-Gaya B, Etxebarria N. Optimization for the analysis of 42 per- and polyfluorinated substances in human plasma: A high-throughput method for epidemiological studies. J Chromatogr A. 2023 Dec 6;1712:464481. PMID: 37948771


Crecimiento postnatal y Obesidad -
Salud reproductiva -


Associations of Maternal Educational Level, Proximity to Greenspace During Pregnancy, and Gestational Diabetes With Body Mass Index From Infancy to Early Adulthood: A Proof-of-Concept Federated Analysis in 18 Birth Cohorts

Cadman T, Elhakeem A, Vinther JL, Avraam D, Carrasco P, Calas L, Cardo M, Charles MA, Corpeleijn E, Crozier S, de Castro M, Estarlich M, Fernandes A, Fossatti S, Gruszfeld D, Gurlich K, Grote V, Haakma S, Harris JR, Heude B, Huang RC, Ibarluzea J, Inskip H, Jaddoe V, Koletzko B, Luque V, Manios Y, Moirano G, Moschonis G, Nader J, Nieuwenhuijsen M, Andersen AN, McEachen R, de Moira AP, Popovic M, Roumeliotaki T, Salika T, Marina LS, Santos S, Serbert S, Tzorovili E, Vafeiadi M, Verduci E, Vrijheid M, Vrijkotte TGM, Welten M, Wright J, Yang TC, Zugna D, Lawlor D. Associations of Maternal Educational Level, Proximity to Greenspace During Pregnancy, and Gestational Diabetes With Body Mass Index From Infancy to Early Adulthood: A Proof-of-Concept Federated Analysis in 18 Birth Cohorts. Am J Epidemiol. 2024-2023 Oct 19:kwad206. doi: 10.1093/aje/kwad206. Epub ahead of print. PMID: 37856700


Metales -
Neurodesarrollo -


Association of maternal prenatal urinary fluoride levels with ADHD symptoms in childhood

Ibarluzea J, Subiza-Pérez M, Arregi A, Molinuevo A, Arranz-Freijo E, Sánchez-de Miguel M, Jiménez A, Andiarena A, Santa-Marina L, Lertxundi A. Association of maternal prenatal urinary fluoride levels with ADHD symptoms in childhood. Environ Res. 2023 Oct 15;235:116705. PMID: 37479215


Exposoma -
Vitamina D -


Sociodemographic, lifestyle, and environmental determinants of vitamin D levels in pregnant women in Spain

Llopis M, Ventura PS, Brachowicz N, Sangüesa J, Murcia M, Lopez-Espinosa MJ, García-Baquero G, Lertxundi A, Vrijheid M, Casas M, Petrone P. Sociodemographic, lifestyle, and environmental determinants of vitamin D levels in pregnant women in Spain. Environ Int. 2023 Dec;182:108293. PMID: 37984291


Neurodesarrollo -
Problemas del sueño -


Sleep problems at ages 8-9 and ADHD symptoms at ages 10-11: evidence in three cohorts from INMA study

González-Safont L, Rebagliato M, Arregi A, Carrasco P, Guxens M, Vegas O, Julvez J, Estarlich M. Sleep problems at ages 8-9 and ADHD symptoms at ages 10-11: evidence in three cohorts from INMA study. Eur J Pediatr. 2023 Nov;182(11):5211-5222. PMID: 37721582


Compuestos tóxicos no persistentes -
Compuestos tóxicos persistentes -
Crecimiento postnatal y Obesidad -


Prenatal Exposure to Multiple Endocrine-Disrupting Chemicals and Childhood BMI Trajectories in the INMA Cohort Study

Montazeri P, Güil-Oumrait N, Marquez S, Cirugeda L, Beneito A, Guxens M, Lertxundi A, Lopez-Espinosa MJ, Santa-Marina L, Sunyer J, Casas M, Vrijheid M. Prenatal Exposure to Multiple Endocrine-Disrupting Chemicals and Childhood BMI Trajectories in the INMA Cohort Study. Environ Health Perspect. 2023 Oct;131(10):107006. PMID: 37850789


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