Gipuzkoa
2006ko maiatzean, “Haurtzaroa eta Ingurumena” (INMA) proiektua jarri zen martxan Gipuzkoan. Helburu nagusia zen airean, uretan eta dietan aurkitzen diren ingurumen-kutsatzaileek haurren hazkuntzan etagarapenean izan dezaketen eragina aztertzea. Emakumeak haurdunaldiko kontrolaren lehen ekografia egitean sartzen dira kohortean.Lagin biologikoak (odola, gernua, ilea, plazenta, eta abar) jasotzeaz gain, zenbait galdesorta (orokorra, dietaz, lanaz, ingurugiroaz, eta abar) betetzen dira, batetik, airean, ingurugiroan eta kontsumoko uretan aurkitzen diren kutsatzaileen balorazioa egiteko, eta, bestetik, dieta bidez jasotako kutsatzaileen estimazioa ateratzeko.
Zumarragako Ospitaleari dagokion biztanleriak definitzen du ikerketaren inguru geografikoa, hau da, Goierriko eta Urola Garaiko nahiz Urola Erdiko udalerriak. Inguru hori aukeratu zen, hain zuen, lehen mailako arreta eskaintzeagatik eta ospitaleko zerbitzuen ezaugarriengatik, eta baita ingurumen ezaugarriengatik ere: industria siderometalurgiko ugaria, zirkulazio-dentsitate altua, desinfektatzetik eratorritako produktuen maila baxua edateko uretan, arrain ugariko dieta, eta, horiekin batera, hipotiroidismo pixka bat emakume haurdunengan.
Orduz geroztik, 640 emakumeren jarraipena egin da haurdunaldiaren lehenengo eta hirugarren hilabeteetan. Gaur egun, 623 haurren jarraipena egiten ari gara hazkuntzaren eta garapen neurokonduktualaren gainean.
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Financiadores de la cohorte INMA-Gipuzkoa:
This study was funded by grants from Instituto de Salud Carlos III (FIS-PI06/0867, FIS-PI09/00090, FIS-PI13/02187 and FIS-PI18/01142 incl. FEDER funds), CIBERESP, Department of Health of the Basque Government (2005111093, 2009111069, 2013111089 and 2015111065), and the Provincial Government of Gipuzkoa (DFG06/002, DFG08/001 and DFG15/221) and annual agreements with the municipalities of the study area (Zumarraga, Urretxu, Ordizia, Legazpi, Azkoitia y Azpeitia y Beasain).
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Entidades Colaboradoras:
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Prenatal Exposure to DDE and PCB 153 and Respiratory Health in Early Childhood: A Meta-Analysis
Gascon M, Sunyer J, Casas M, Martínez D, Ballester F, Basterrechea M, Bonde JP, Chatzi L, Chevrier C, Eggesbø M, Esplugues A, Govarts E, Hannu K, Ibarluzea J, Kasper-Sonnenberg M, Klümper C, Koppen G, Nieuwenhuijsen MJ, Palkovicova L, Pelé F, Polder. Prenatal Exposure to DDE and PCB 153 and Respiratory Health in Early Childhood: A Meta-Analysis. Epidemiology. 2014 Jul;25(4):544-53. PMID: 24776790
Preterm birth, infant weight gain, and childhood asthma risk: A meta-analysis of 147,000 European children
Sonnenschein-van der Voort AM, Arends LR, de Jongste JC, Annesi-Maesano I, Arshad SH, Barros H, Basterrechea M, Bisgaard H, Chatzi L, Corpeleijn E, Correia S, Craig LC, Devereux G, Dogaru C, Dostal M, Duchen K, Eggesbø M, van der Ent CK, Fantini MP. Preterm birth, infant weight gain, and childhood asthma risk: A meta-analysis of 147,000 European children. J Allergy Clin Immunol. 2014 May;133(5):1317-29. PMID: 24529685
Fish intake during pregnancy, fetal growth, and gestational length in 19 European birth cohort studies
Leventakou V, Roumeliotaki T, Martinez D, Barros H, Brantsaeter AL, Casas M, Charles MA, Cordier S, Eggesbø M, van Eijsden M, Forastiere F, Gehring U, Govarts E, Halldórsson TI, Hanke W, Haugen M, Heppe DH, Heude B, Inskip HM, Jaddoe VW, Jansen M, Ke. Fish intake during pregnancy, fetal growth, and gestational length in 19 European birth cohort studies. Am J Clin Nutr. 2014 Mar;99(3):506-16. PMID: 24335057
The Development of the MeDALL Core Questionnaires for a Harmonized Follow-Up Assessment of Eleven European Birth Cohorts on Asthma and Allergies
Hohmann C, Pinart M, Tischer C, Gehring U, Heinrich J, Kull I, Melén E, Smit HA, Torrent M, Wijga AH, Wickman M, Bachert C, Lødrup Carlsen KC, Carlsen KH, Bindslev-Jensen C, Eller E, Esplugues A, Fantini MP, Annesi-Maesano I, Momas I, Porta D, Vassil. The Development of the MeDALL Core Questionnaires for a Harmonized Follow-Up Assessment of Eleven European Birth Cohorts on Asthma and Allergies. Int Arch Allergy Immunol. 2014;163(3):215-24. PMID: 24642608
Air Polycyclic Aromatic Hydrocarbons (PAHs) associated with PM2.5 in a North Cantabric coast urban environment
Villar-Vidal M, Lertxundi A, Martinez López de Dicastillo MD, Alvarez JI, Santa Marina L, Ayerdi M, Basterrechea M, Ibarluzea J. Air Polycyclic Aromatic Hydrocarbons (PAHs) associated with PM2.5 in a North Cantabric coast urban environment. Chemosphere. 2014 Mar;99:233-8. PMID: 24331032
Air Pollution and Respiratory Infections during Early Childhood: An Analysis of 10 European Birth Cohorts within the ESCAPE Project
Macintyre EA, Gehring U, Mölter A, Fuertes E, Klümper C, Krämer U, Quass U, Hoffmann B, Gascon M, Brunekreef B, Koppelman GH, Beelen R, Hoek G, Birk M, de Jongste JC, Smit H, Cyrys J, Gruzieva O, Korek M, Bergström A, Agius RM, de Vocht F, Simpson A. Air Pollution and Respiratory Infections during Early Childhood: An Analysis of 10 European Birth Cohorts within the ESCAPE Project. Environ Health Perspect. 2014 Jan;122(1):107-13. PMID: 24149084
Prenatal exposure to persistent organic pollutants and rapid weight gain and overweight in infancy
Valvi D, Mendez MA, Garcia-Esteban R, Ballester F, Ibarluzea J, Goñi F, Grimalt JO, Llop S, Marina LS, Vizcaino E, Sunyer J, Vrijheid M. Prenatal exposure to persistent organic pollutants and rapid weight gain and overweight in infancy. Obesity (Silver Spring). 2014 Feb;22(2):488-96. PMID: 23963708
Epidemiologic Tools to Study the Influence of Environmental Factors on Fecundity and Pregnancy-related Outcomes
Slama R, Ballester F, Casas M, Cordier S, Eggesbø M, Iniguez C, Nieuwenhuijsen M, Philippat C, Rey S, Vandentorren S, Vrijheid M. Epidemiologic Tools to Study the Influence of Environmental Factors on Fecundity and Pregnancy-related Outcomes. Epidemiol Rev. 2014;36(1):148-64. PMID: 24363355
Prenatal exposure to hexachlorobenzene (HCB) and reproductive effects in a multicentre birth cohort in Spain
Basterrechea M, Lertxundi A, Iñiguez C, Mendez M, Murcia M, Mozo I, Goñi F, Grimalt J, Fernández M, Guxens M; INMA project. Prenatal exposure to hexachlorobenzene (HCB) and reproductive effects in a multicentre birth cohort in Spain. Sci Total Environ. 2014 Jan 1;466-467:770-6. PMID: 23973543
Factors associated with second-hand smoke exposure in non-smoking pregnant women in Spain: Self-reported exposure and urinary cotinine levels
Aurrekoetxea JJ, Murcia M, Rebagliato M, Fernández-Somoano A, Castilla AM, Guxens M, López MJ, Lertxundi A, Espada M, Tardón A, Ballester F, Santa-Marina L. Factors associated with second-hand smoke exposure in non-smoking pregnant women in Spain: Self-reported exposure and urinary cotinine levels. Sci Total Environ. 2014 Feb 1;470-471:1189-96. PMID: 24246942
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