Gipuzkoa
2006ko maiatzean, “Haurtzaroa eta Ingurumena” (INMA) proiektua jarri zen martxan Gipuzkoan. Helburu nagusia zen airean, uretan eta dietan aurkitzen diren ingurumen-kutsatzaileek haurren hazkuntzan etagarapenean izan dezaketen eragina aztertzea. Emakumeak haurdunaldiko kontrolaren lehen ekografia egitean sartzen dira kohortean.Lagin biologikoak (odola, gernua, ilea, plazenta, eta abar) jasotzeaz gain, zenbait galdesorta (orokorra, dietaz, lanaz, ingurugiroaz, eta abar) betetzen dira, batetik, airean, ingurugiroan eta kontsumoko uretan aurkitzen diren kutsatzaileen balorazioa egiteko, eta, bestetik, dieta bidez jasotako kutsatzaileen estimazioa ateratzeko.
Zumarragako Ospitaleari dagokion biztanleriak definitzen du ikerketaren inguru geografikoa, hau da, Goierriko eta Urola Garaiko nahiz Urola Erdiko udalerriak. Inguru hori aukeratu zen, hain zuen, lehen mailako arreta eskaintzeagatik eta ospitaleko zerbitzuen ezaugarriengatik, eta baita ingurumen ezaugarriengatik ere: industria siderometalurgiko ugaria, zirkulazio-dentsitate altua, desinfektatzetik eratorritako produktuen maila baxua edateko uretan, arrain ugariko dieta, eta, horiekin batera, hipotiroidismo pixka bat emakume haurdunengan.
Orduz geroztik, 640 emakumeren jarraipena egin da haurdunaldiaren lehenengo eta hirugarren hilabeteetan. Gaur egun, 623 haurren jarraipena egiten ari gara hazkuntzaren eta garapen neurokonduktualaren gainean.
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Financiadores de la cohorte INMA-Gipuzkoa:
This study was funded by grants from Instituto de Salud Carlos III (FIS-PI06/0867, FIS-PI09/00090, FIS-PI13/02187 and FIS-PI18/01142 incl. FEDER funds), CIBERESP, Department of Health of the Basque Government (2005111093, 2009111069, 2013111089 and 2015111065), and the Provincial Government of Gipuzkoa (DFG06/002, DFG08/001 and DFG15/221) and annual agreements with the municipalities of the study area (Zumarraga, Urretxu, Ordizia, Legazpi, Azkoitia y Azpeitia y Beasain).
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Entidades Colaboradoras:
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Characterisation of exposure to non-ionising electromagnetic fields in the Spanish INMA birth cohort: study protocol
Gallastegi M, Guxens M, Jiménez-Zabala A, Calvente I, Fernández M, Birks L, Struchen B, Vrijheid M, Estarlich M, Fernández MF, Torrent M, Ballester F, Aurrekoetxea JJ, Ibarluzea J, Guerra D, González J, Röösli M, Santa-Marina L. Characterisation of exposure to non-ionising electromagnetic fields in the Spanish INMA birth cohort: study protocol. BMC Public Health. 2016 Feb 18;16(1):167. PMID: 26892951
Air Pollution Exposure during Pregnancy and Childhood Autistic Traits in Four European Population-Based Cohort Studies: The ESCAPE Project
Guxens M, Ghassabian A, Gong T, Garcia-Esteban R, Porta D, Giorgis-Allemand L, Almqvist C, Aranbarri A, Beelen R, Badaloni C, Cesaroni G, de Nazelle A, Estarlich M, Forastiere F, Forns J, Gehring U, Ibarluzea J, Jaddoe VW, Korek M, Lichtenstein P, Ni. Air Pollution Exposure during Pregnancy and Childhood Autistic Traits in Four European Population-Based Cohort Studies: The ESCAPE Project. Environ Health Perspect. 2016 Jan;2016(1):133-40. PMID: 26068947
Organochlorine Compounds and Ultrasound Measurements of Fetal Growth in the INMA Cohort (Spain)
Lopez-Espinosa MJ, Murcia M, Iñiguez C, Vizcaino E, Costa O, Fernández-Somoano A, Basterrechea M, Lertxundi A, Guxens M, Gascon M, Goñi-Irigoyen F, Grimalt JO, Tardón A, Ballester F. Organochlorine Compounds and Ultrasound Measurements of Fetal Growth in the INMA Cohort (Spain). Environ Health Perspect. 2016 Jan;2016(1):157-63. PMID: 26058084
Use of high doses of folic acid supplements in pregnant women in Spain: an INMA cohort study
Navarrete-Muñoz EM, Valera-Gran D, García de la Hera M, Gimenez-Monzo D, Morales E, Julvez J, Riaño I, Tardón A, Ibarluzea J, Santa-Marina L, Murcia M, Rebagliato M, Vioque J; INMA Project. Use of high doses of folic acid supplements in pregnant women in Spain: an INMA cohort study. BMJ Open. 2015 Nov 24;5(11):e009202. doi: 10.1136/bmjopen-2015-009202. PMID: 26603248
Water hardness and eczema at 1 and 4y of age in the INMA birth cohort
Font-Ribera L, Gracia-Lavedan E, Esplugues A, Ballester F, Jiménez Zabala A, Santa Marina L, Fernández-Somoano A, Sunyer J, Villanueva CM. Water hardness and eczema at 1 and 4y of age in the INMA birth cohort. Environ Res. 2015 Oct;142:579-85.P MID: 26298601
Transfer of perfluoroalkyl substances from mother to fetus in a Spanish birth cohort
Manzano-Salgado CB, Casas M, Lopez-Espinosa MJ, Ballester F, Basterrechea M, Grimalt JO, Jiménez AM, Kraus T, Schettgen T, Sunyer J, Vrijheid M. Transfer of perfluoroalkyl substances from mother to fetus in a Spanish birth cohort. Environ Res.2015 Oct;142:471-8. PMID: 26257032
Mother’s education and the risk of preterm and small for gestational age birth: a DRIVERS meta-analysis of 12 European cohorts
Ruiz M, Goldblatt P, Morrison J, Kukla L, Švancara J, Riitta-Järvelin M, Taanila A, Saurel-Cubizolles MJ, Lioret S, Bakoula C, Veltsista A, Porta D, Forastiere F, van Eijsden M, Vrijkotte TG, Eggesbø M, White RA, Barros H, Correia S, Vrijheid M, Torr. Mother’s education and the risk of preterm and small for gestational age birth: a DRIVERS meta-analysis of 12 European cohorts. J Epidemiol Community Health. 2015 Sep;69(9):826-33. PMID: 25911693
Associations of maternal circulating 25-hydroxyvitamin D3 concentration with pregnancy and birth outcomes
Rodriguez A, García-Esteban R, Basterretxea M, Lertxundi A, Rodríguez-Bernal C, Iñiguez C, Rodriguez-Dehli C, Tardón A, Espada M, Sunyer J, Morales E. Associations of maternal circulating 25-hydroxyvitamin D3 concentration with pregnancy and birth outcomes. BJOG. 2015 Nov;122(12):1695-704. PMID: 25208685
Exploring educational disparities in risk of preterm delivery: a comparative study of 12 European birth cohorts
Poulsen G, Strandberg-Larsen K, Mortensen L, Barros H, Cordier S, Correia S, Danileviciute A, van Eijsden M, Fernández-Somoano A, Gehring U, Grazuleviciene R, Hafkamp-de Groen E, Henriksen TB, Jensen MS, Larrañaga I, Magnus P, Pickett K, Raat H, Rich. Exploring educational disparities in risk of preterm delivery: a comparative study of 12 European birth cohorts. Paediatr Perinat Epidemiol. 2015 May;29(3):172-83. PMID: 25808200
Exposure to fine particle matter, nitrogen dioxide and benzene during pregnancy and cognitive and psychomotor developments in children at 15months of age
Lertxundi A, Baccini M, Lertxundi N, Fano E, Aranbarri A, Martínez MD, Ayerdi M, Álvarez J, Santa-Marina L, Dorronsoro M, Ibarluzea J. Exposure to fine particle matter, nitrogen dioxide and benzene during pregnancy and cognitive and psychomotor developments in children at 15months of age. Environ Int. 2015 Jul;80:33-40. PMID: 25881275
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