Gipuzkoa
2006ko maiatzean, “Haurtzaroa eta Ingurumena” (INMA) proiektua jarri zen martxan Gipuzkoan. Helburu nagusia zen airean, uretan eta dietan aurkitzen diren ingurumen-kutsatzaileek haurren hazkuntzan etagarapenean izan dezaketen eragina aztertzea. Emakumeak haurdunaldiko kontrolaren lehen ekografia egitean sartzen dira kohortean.Lagin biologikoak (odola, gernua, ilea, plazenta, eta abar) jasotzeaz gain, zenbait galdesorta (orokorra, dietaz, lanaz, ingurugiroaz, eta abar) betetzen dira, batetik, airean, ingurugiroan eta kontsumoko uretan aurkitzen diren kutsatzaileen balorazioa egiteko, eta, bestetik, dieta bidez jasotako kutsatzaileen estimazioa ateratzeko.
Zumarragako Ospitaleari dagokion biztanleriak definitzen du ikerketaren inguru geografikoa, hau da, Goierriko eta Urola Garaiko nahiz Urola Erdiko udalerriak. Inguru hori aukeratu zen, hain zuen, lehen mailako arreta eskaintzeagatik eta ospitaleko zerbitzuen ezaugarriengatik, eta baita ingurumen ezaugarriengatik ere: industria siderometalurgiko ugaria, zirkulazio-dentsitate altua, desinfektatzetik eratorritako produktuen maila baxua edateko uretan, arrain ugariko dieta, eta, horiekin batera, hipotiroidismo pixka bat emakume haurdunengan.
Orduz geroztik, 640 emakumeren jarraipena egin da haurdunaldiaren lehenengo eta hirugarren hilabeteetan. Gaur egun, 623 haurren jarraipena egiten ari gara hazkuntzaren eta garapen neurokonduktualaren gainean.
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Financiadores de la cohorte INMA-Gipuzkoa:
This study was funded by grants from Instituto de Salud Carlos III (FIS-PI06/0867, FIS-PI09/00090, FIS-PI13/02187 and FIS-PI18/01142 incl. FEDER funds), CIBERESP, Department of Health of the Basque Government (2005111093, 2009111069, 2013111089 and 2015111065), and the Provincial Government of Gipuzkoa (DFG06/002, DFG08/001 and DFG15/221) and annual agreements with the municipalities of the study area (Zumarraga, Urretxu , Legazpi, Azkoitia y Azpeitia y Beasain).
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Entidades Colaboradoras:
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Urban environment in pregnancy and postpartum depression: An individual participant data meta-analysis of 12 European birth cohorts
Cadman T, Strandberg-Larsen K, Calas L, Christiansen M, Culpin I, Dadvand P, de Castro M, Foraster M, Fossati S, Guxens M, Harris JR, Hillegers M, Jaddoe V, Lee Y, Lepeule J, El Marroun H, Maule M, McEachen R, Moccia C, Nader J, Nieuwenhuijsen M, Nybo Andersen AM, Pearson R, Swertz M, Vafeiadi M, Vrijheid M, Wright J, Lawlor DA, Pedersen M. Urban environment in pregnancy and postpartum depression: An individual participant data meta-analysis of 12 European birth cohorts. Environ Int. 2024 Mar;185:108453. PMID: 38368715
Association between telomere length and neuropsychological function at 4-5 years in children from the INMA project: a cross-sectional study
Campos-Sánchez I, Navarrete-Muñoz EM, Hurtado-Pomares M, Júlvez J, Lertxundi N, Martens DS, Fernández-Somoano A, Riaño-Galán I, Guxens M, Ibarluzea JM, Nawrot T, Valera-Gran D. Association between telomere length and neuropsychological function at 4-5 years in children from the INMA project: a cross-sectional study. Eur Child Adolesc Psychiatry. 2024 Aug;33(8):2803-2812. PMID: 38246982
Susceptible windows of prenatal and postnatal fine particulate matter exposures and attention-deficit hyperactivity disorder symptoms in early childhood
Chen WJ, Rector-Houze AM, Guxens M, Iñiguez C, Swartz MD, Symanski E, Ibarluzea J, Valentin A, Lertxundi A, González-Safont L, Sunyer J, Whitworth KW. Susceptible windows of prenatal and postnatal fine particulate matter exposures and attention-deficit hyperactivity disorder symptoms in early childhood. Sci Total Environ. 2024 Feb 20;912:168806. PMID: 38016567
Relation of prenatal and postnatal PM2.5 exposure with cognitive and motor function among preschool-aged children
Whitworth KW, Rector-Houze AM, Chen WJ, Ibarluzea J, Swartz M, Symanski E, Iniguez C, Lertxundi A, Valentin A, González-Safont L, Vrijheid M, Guxens M. Relation of prenatal and postnatal PM2.5 exposure with cognitive and motor function among preschool-aged children. Int J Hyg Environ Health. 2024 Mar;256:114317. PMID: 38171265
Mediators of the association between maternal body mass index and breastfeeding duration in 3 international cohorts
Keyes M, Andrews C, Midya V, Carrasco P, Guxens M, Jimeno-Romero A, Murcia M, Rodriguez-Dehli C, Romaguera D, Santa-Maria L, Vafeiadi M, Chatzi L, Oken E, Vrijheid M, Valvi D, Sen S. Mediators of the association between maternal body mass index and breastfeeding duration in 3 international cohorts. Am J Clin Nutr. 2023 Jul;118(1):255-263. PMID: 37407164
Association between relative age at school and persistence of ADHD in prospective studies: an individual participant data meta-analysis
Synergy for the Influence of the Month of Birth in ADHD (SIMBA) study group. Association between relative age at school and persistence of ADHD in prospective studies: an individual participant data meta-analysis. Lancet Psychiatry. 2023 Dec;10(12):922-933. PMID: 37898142
Susceptible windows of exposure to fine particulate matter and fetal growth trajectories in the Spanish INMA (INfancia y Medio Ambiente) birth cohort
Chen WJ, Rector AM, Guxens M, Iniguez C, Swartz MD, Symanski E, Ibarluzea J, Ambros A, Estarlich M, Lertxundi A, Riano-Galán I, Sunyer J, Fernandez-Somoano A, Chauhan SP, Ish J, Whitworth KW. Susceptible windows of exposure to fine particulate matter and fetal growth trajectories in the Spanish INMA (INfancia y Medio Ambiente) birth cohort. Environ Res. 2023 Jan 1;216(Pt 2):114628. PMID: 36279916
Social inequalities, green and blue spaces and mental health in 6-12 years old children participating in the INMA cohort
Subiza-Pérez M, García-Baquero G, Fernández-Somoano A, Riaño I, González L, Delgado-Saborit JM, Guxens M, Fossati S, Vrijheid M, Fernandes A, Ibarluzea J, Lertxundi N. Social inequalities, green and blue spaces and mental health in 6-12 years old children participating in the INMA cohort. Health Place. 2023 Sep;83:103104. PMID: 37611380
Residential green and blue spaces and working memory in children aged 6-12 years old. Results from the INMA cohort
Subiza-Pérez M, García-Baquero G, Fernández-Somoano A, Guxens M, González L, Tardón A, Dadvand P, Estarlich M, de Castro M, McEachan RRC, Ibarluzea J, Lertxundi N. Residential green and blue spaces and working memory in children aged 6-12 years old. Results from the INMA cohort. Health Place. 2023 Nov;84:103136. PMID: 37871446
Optimization for the analysis of 42 per- and polyfluorinated substances in human plasma: A high-throughput method for epidemiological studies
San Román A, Abilleira E, Irizar A, Santa-Marina L, Gonzalez-Gaya B, Etxebarria N. Optimization for the analysis of 42 per- and polyfluorinated substances in human plasma: A high-throughput method for epidemiological studies. J Chromatogr A. 2023 Dec 6;1712:464481. PMID: 37948771
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