Gipuzkoa
2006ko maiatzean, “Haurtzaroa eta Ingurumena” (INMA) proiektua jarri zen martxan Gipuzkoan. Helburu nagusia zen airean, uretan eta dietan aurkitzen diren ingurumen-kutsatzaileek haurren hazkuntzan etagarapenean izan dezaketen eragina aztertzea. Emakumeak haurdunaldiko kontrolaren lehen ekografia egitean sartzen dira kohortean.Lagin biologikoak (odola, gernua, ilea, plazenta, eta abar) jasotzeaz gain, zenbait galdesorta (orokorra, dietaz, lanaz, ingurugiroaz, eta abar) betetzen dira, batetik, airean, ingurugiroan eta kontsumoko uretan aurkitzen diren kutsatzaileen balorazioa egiteko, eta, bestetik, dieta bidez jasotako kutsatzaileen estimazioa ateratzeko.
Zumarragako Ospitaleari dagokion biztanleriak definitzen du ikerketaren inguru geografikoa, hau da, Goierriko eta Urola Garaiko nahiz Urola Erdiko udalerriak. Inguru hori aukeratu zen, hain zuen, lehen mailako arreta eskaintzeagatik eta ospitaleko zerbitzuen ezaugarriengatik, eta baita ingurumen ezaugarriengatik ere: industria siderometalurgiko ugaria, zirkulazio-dentsitate altua, desinfektatzetik eratorritako produktuen maila baxua edateko uretan, arrain ugariko dieta, eta, horiekin batera, hipotiroidismo pixka bat emakume haurdunengan.
Orduz geroztik, 640 emakumeren jarraipena egin da haurdunaldiaren lehenengo eta hirugarren hilabeteetan. Gaur egun, 623 haurren jarraipena egiten ari gara hazkuntzaren eta garapen neurokonduktualaren gainean.
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Financiadores de la cohorte INMA-Gipuzkoa:
This study was funded by grants from Instituto de Salud Carlos III (FIS-PI06/0867, FIS-PI09/00090, FIS-PI13/02187 and FIS-PI18/01142 incl. FEDER funds), CIBERESP, Department of Health of the Basque Government (2005111093, 2009111069, 2013111089 and 2015111065), and the Provincial Government of Gipuzkoa (DFG06/002, DFG08/001 and DFG15/221) and annual agreements with the municipalities of the study area (Zumarraga, Urretxu, Ordizia, Legazpi, Azkoitia y Azpeitia y Beasain).
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Entidades Colaboradoras:
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Early-life growth and emotional, behavior and cognitive outcomes in childhood and adolescence in the EU child cohort network: individual participant data meta-analysis of over 109,000 individuals
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Windows of susceptibility of prenatal and childhood exposure to air pollution and lung function at 6-8 years in the Spanish INMA (INfancia y Medio Ambiente) birth cohort
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Impact of pet ownership in early childhood at ages 1 and 4-5 years on mental health at ages 7-8: findings from the INMA project
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Investigating the relationship between neighbourhood characteristics, perceived social support and psychological wellbeing in Spanish adolescents
Piera Pi-Sunyer B, Bignardi G, García-Baquero G, Dadvand P, Vrijheid M, Guxens M, Esplugues A, Delgado-Saborit JM, Ibarluzea J, Blakemore SJ, Subiza-Pérez M. Investigating the relationship between neighbourhood characteristics, perceived social support and psychological wellbeing in Spanish adolescents. Sci Rep. 2025 Nov 6;15(1):38845. PMID: 41198832
Association between early-life exposure to mercury and cardiometabolic risk factors development in adolescence
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Assessing metal mixture effects on neuropsychological development: A trade-off between complexity and interpretability
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Exposure to high temperature and sleep in preadolescents from two European birth cohorts
Essers E, Granés L, Botella N, Petricola S, González-Safont L, Arregi A, Vegas O, Vrijheid M, Iñiguez C, El Marroun H, Tiemeier H, Guxens M. Exposure to high temperature and sleep in preadolescents from two European birth cohorts. Environ Int. 2025 Jun;200:109543. PMID: 40424701
Mixtures of chemicals in pregnancy and their effects on cognitive and fine motor abilities in childhood
Brennan Kearns P, González L, Soler-Blasco R, Andiarena A, Santa-Marina L, Casas M, Burgaleta M, Vrijheid M, Guxens M. Mixtures of chemicals in pregnancy and their effects on cognitive and fine motor abilities in childhood. Environ Res. 2025 Nov 15;285(Pt 2):122380. PMID: 40692023
Seroepidemiology of maternal and childhood pathogen exposure in three European mother-child cohorts
Karachaliou M, Vidal M, Pembrey L, Bustamante M, Espinosa A, Mason D, Bañuls M, Casabonne D, Roumeliotaki T, Bempi V, Marin N, Delgado-Saborit JM, Loreto SMR, Ibarluzea J, Vrijheid M, Aguilar R, Dobaño C, Kogevinas M. Seroepidemiology of maternal and childhood pathogen exposure in three European mother-child cohorts. Int J Infect Dis. 2025 Oct;159:107994. PMID: 40701399
Maternal nut and fish consumption during pregnancy and child risky decision-making at 11 years old
Rivera MR, Pinar-Martí A, Babarro I, Ibarluzea J, Vioque J, Llop S, Fernández-Somoano A, Tardón A, Pascual-Rubio V, Fabregat-Sanjuan A, Fernández-Barrés S, Romaguera D, Guxens M, Julvez J. Maternal nut and fish consumption during pregnancy and child risky decision-making at 11 years old. Eur Child Adolesc Psychiatry. 2025 Nov;34(11):3643-3654. PMID: 40493090. Comment: Eur Child Adolesc Psychiatry. 2026 Jan;35(1):295-296. PMID: 40928651. Response: Eur Child Adolesc Psychiatry. 2026 Jan;35(1):301-302. PMID: 41042371
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