Gipuzkoa
2006ko maiatzean, “Haurtzaroa eta Ingurumena” (INMA) proiektua jarri zen martxan Gipuzkoan. Helburu nagusia zen airean, uretan eta dietan aurkitzen diren ingurumen-kutsatzaileek haurren hazkuntzan etagarapenean izan dezaketen eragina aztertzea. Emakumeak haurdunaldiko kontrolaren lehen ekografia egitean sartzen dira kohortean.Lagin biologikoak (odola, gernua, ilea, plazenta, eta abar) jasotzeaz gain, zenbait galdesorta (orokorra, dietaz, lanaz, ingurugiroaz, eta abar) betetzen dira, batetik, airean, ingurugiroan eta kontsumoko uretan aurkitzen diren kutsatzaileen balorazioa egiteko, eta, bestetik, dieta bidez jasotako kutsatzaileen estimazioa ateratzeko.
Zumarragako Ospitaleari dagokion biztanleriak definitzen du ikerketaren inguru geografikoa, hau da, Goierriko eta Urola Garaiko nahiz Urola Erdiko udalerriak. Inguru hori aukeratu zen, hain zuen, lehen mailako arreta eskaintzeagatik eta ospitaleko zerbitzuen ezaugarriengatik, eta baita ingurumen ezaugarriengatik ere: industria siderometalurgiko ugaria, zirkulazio-dentsitate altua, desinfektatzetik eratorritako produktuen maila baxua edateko uretan, arrain ugariko dieta, eta, horiekin batera, hipotiroidismo pixka bat emakume haurdunengan.
Orduz geroztik, 640 emakumeren jarraipena egin da haurdunaldiaren lehenengo eta hirugarren hilabeteetan. Gaur egun, 623 haurren jarraipena egiten ari gara hazkuntzaren eta garapen neurokonduktualaren gainean.
-
Financiadores de la cohorte INMA-Gipuzkoa:
This study was funded by grants from Instituto de Salud Carlos III (FIS-PI06/0867, FIS-PI09/00090, FIS-PI13/02187 and FIS-PI18/01142 incl. FEDER funds), CIBERESP, Department of Health of the Basque Government (2005111093, 2009111069, 2013111089 and 2015111065), and the Provincial Government of Gipuzkoa (DFG06/002, DFG08/001 and DFG15/221) and annual agreements with the municipalities of the study area (Zumarraga, Urretxu , Legazpi, Azkoitia y Azpeitia y Beasain).
-
Entidades Colaboradoras:
Search
Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults
NCD Risk Factor Collaboration (NCD-RisC). Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults. Lancet. 2024 Mar 16;403(10431):1027-1050. PMID: 38432237
Early childcare arrangements and children’s internalizing and externalizing symptoms: an individual participant data meta-analysis of six prospective birth cohorts in Europe
Barry KM, Avraam D, Cadman T, Elhakeem A, El Marroun H, Jansen PW, Nybo-Andersen AM, Strandberg-Larsen K, Safont LG, Soler-Blasco R, Barreto-Zarza F, Julvez J, Vrijheid M, Heude B, Charles MA, Gomajee AR, Melchior M. Early childcare arrangements and children’s internalizing and externalizing symptoms: an individual participant data meta-analysis of six prospective birth cohorts in Europe. Lancet Reg Health Eur. 2024 Aug 21;45:101036. PMID: 39262448
Socioeconomic position during pregnancy and pre-school exposome in children from eight European birth cohort studies
Pizzi C, Moirano G, Moccia C, Maule M, D’Errico A, Vrijheid M, Cadman TJ, Fossati S, Nieuwenhuijsen M, Beneito A, Calas L, Duijts L, Elhakeem A, Harris JR, Heude B, Jaddoe V, Lawlor DA, Lioret S, McEachan RR, Nader JL, Pedersen M, Pinot de Moira A, Strandberg-Larsen K, Subiza-Pérez M, Vafeiadi M, Welten M, Wright J, Yang TC, Richiardi L. Socioeconomic position during pregnancy and pre-school exposome in children from eight European birth cohort studies. Soc Sci Med. 2024 Oct;359:117275. PMID: 39236481
Urban environment exposures, energy balance-related behaviors and their combination in preschoolers from three European countries
Descarpentrie A, Dargent-Molina P, Arregi A, Carrasco P, Estarlich M, Guxens M, McEachan R, Nieuwenhuijsen M, Subiza-Pérez M, Wright J, Charles MA, Heude B, Vrijheid M, Lioret S. Urban environment exposures, energy balance-related behaviors and their combination in preschoolers from three European countries. Environ Int. 2024 Aug;190:108880. PMID: 39024825
Association of Gestational Free and Total Triiodothyronine With Gestational Hypertension, Preeclampsia, Preterm Birth, and Birth Weight: An Individual Participant Data Meta-analysis
Derakhshan A, Männistö T, Chen L, Osinga JAJ, Ashoor G, Lu X, Bliddal S, Tao FB, Brown SJ, Vaidya B, Hattersley AT, Itoh S, Popova PV, Aminorroaya A, Kishi R, Kianpour M, Vasukova EA, López-Bermejo A, Oken E, Chatzi L, Vafeiadi M, Bramer WM, Bassols J, Lertxundi A, Fernández-Somoano A, Carrasco P, Auvinen J, Huang K, Feldt-Rasmussen U, Grineva EN, Alexander EK, Pearce EN, Chaker L, Walsh JP, Peeters RP, Guxens M, Suvanto E, Nicolaides KH, Korevaar TIM. Association of Gestational Free and Total Triiodothyronine With Gestational Hypertension, Preeclampsia, Preterm Birth, and Birth Weight: An Individual Participant Data Meta-analysis. J Clin Endocrinol Metab. 2024 Feb 20;109(3):e1290-e1298. PMID: 37878891
Hair cortisol determinants in 11-year-old children: Environmental, social and individual factors
Arregi A, Vegas O, Lertxundi A, García-Baquero G, Ibarluzea J, Andiarena A, Babarro I, Subiza-Pérez M, Lertxundi N. Hair cortisol determinants in 11-year-old children: Environmental, social and individual factors. Horm Behav. 2024 Aug;164:105575. PMID: 38851169
Pro-vegetarian dietary patterns and essential and heavy metal exposure in children of 4-5-years from the INfancia y medio Ambiente cohort (INMA)
Oncina-Cánovas A, Vioque J, Riutort-Mayol G, Soler-Blasco R, Irizar A, Barroeta Z, Fernández-Somoano A, Tardón A, Vrijheid M, Guxens M, Carey M, Meharg C, Ralphs K, McCreanor C, Meharg A, Signes-Pastor AJ. Pro-vegetarian dietary patterns and essential and heavy metal exposure in children of 4-5-years from the INfancia y medio Ambiente cohort (INMA). Int J Hyg Environ Health. 2024 Apr;257:114344. PMID: 38430670
Risk Factors for Thyroid Dysfunction in Pregnancy: An Individual Participant Data Meta-Analysis
Osinga JAJ, Liu Y, Männistö T, Vafeiadi M, Tao FB, Vaidya B, Vrijkotte TGM, Mosso L, Bassols J, López-Bermejo A, Boucai L, Aminorroaya A, Feldt-Rasmussen U, Hisada A, Yoshinaga J, Broeren MAC, Itoh S, Kishi R, Ashoor G, Chen L, Veltri F, Lu X, Taylor PN, Brown SJ, Chatzi L, Popova PV, Grineva EN, Ghafoor F, Pirzada A, Kianpour M, Oken E, Suvanto E, Hattersley A, Rebagliato M, Riaño-Galán I, Irizar A, Vrijheid M, Delgado-Saborit JM, Fernández-Somoano A, Santa-Marina L, Boelaert K, Brenta G, Dhillon-Smith R, Dosiou C, Eaton JL, Guan H, Lee SY, Maraka S, Morris-Wiseman LF, Nguyen CT, Shan Z, Guxens M, Pop VJM, Walsh JP, Nicolaides KH, D’Alton ME, Visser WE, Carty DM, Delles C, Nelson SM, Alexander EK, Chaker L, Palomaki GE, Peeters RP, Bliddal S, Huang K, Poppe KG, Pearce EN, Derakhshan A, Korevaar TIM. Risk Factors for Thyroid Dysfunction in Pregnancy: An Individual Participant Data Meta-Analysis. Thyroid. 2024 May;34(5):646-658. PMID: 38546971
Nitrogen dioxide exposure, attentional function, and working memory in children from 4 to 8 years: Periods of susceptibility from pregnancy to childhood
Crooijmans KLHA, Iñiguez C, Withworth KW, Estarlich M, Lertxundi A, Fernández-Somoano A, Tardón A, Ibarluzea J, Sunyer J, Guxens M, Binter AC. Nitrogen dioxide exposure, attentional function, and working memory in children from 4 to 8 years: Periods of susceptibility from pregnancy to childhood. Environ Int. 2024 Apr;186:108604. PMID: 38564945
Evaluating the association between placenta DNA methylation and cognitive functions in the offspring
Diez-Ahijado L, Cilleros-Portet A, Fernández-Jimenez N, Fernández MF, Guxens M, Julvez J, Llop S, Lopez-Espinosa MJ, Subiza-Pérez M, Lozano M, Ibarluzea J, Sunyer J, Bustamante M, Cosin-Tomas M. Evaluating the association between placenta DNA methylation and cognitive functions in the offspring. Transl Psychiatry. 2024 Sep 20;14(1):383. PMID: 39304652
1 / 34
