Gipuzkoa
2006ko maiatzean, “Haurtzaroa eta Ingurumena” (INMA) proiektua jarri zen martxan Gipuzkoan. Helburu nagusia zen airean, uretan eta dietan aurkitzen diren ingurumen-kutsatzaileek haurren hazkuntzan etagarapenean izan dezaketen eragina aztertzea. Emakumeak haurdunaldiko kontrolaren lehen ekografia egitean sartzen dira kohortean.Lagin biologikoak (odola, gernua, ilea, plazenta, eta abar) jasotzeaz gain, zenbait galdesorta (orokorra, dietaz, lanaz, ingurugiroaz, eta abar) betetzen dira, batetik, airean, ingurugiroan eta kontsumoko uretan aurkitzen diren kutsatzaileen balorazioa egiteko, eta, bestetik, dieta bidez jasotako kutsatzaileen estimazioa ateratzeko.
Zumarragako Ospitaleari dagokion biztanleriak definitzen du ikerketaren inguru geografikoa, hau da, Goierriko eta Urola Garaiko nahiz Urola Erdiko udalerriak. Inguru hori aukeratu zen, hain zuen, lehen mailako arreta eskaintzeagatik eta ospitaleko zerbitzuen ezaugarriengatik, eta baita ingurumen ezaugarriengatik ere: industria siderometalurgiko ugaria, zirkulazio-dentsitate altua, desinfektatzetik eratorritako produktuen maila baxua edateko uretan, arrain ugariko dieta, eta, horiekin batera, hipotiroidismo pixka bat emakume haurdunengan.
Orduz geroztik, 640 emakumeren jarraipena egin da haurdunaldiaren lehenengo eta hirugarren hilabeteetan. Gaur egun, 623 haurren jarraipena egiten ari gara hazkuntzaren eta garapen neurokonduktualaren gainean.
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Financiadores de la cohorte INMA-Gipuzkoa:
This study was funded by grants from Instituto de Salud Carlos III (FIS-PI06/0867, FIS-PI09/00090, FIS-PI13/02187 and FIS-PI18/01142 incl. FEDER funds), CIBERESP, Department of Health of the Basque Government (2005111093, 2009111069, 2013111089 and 2015111065), and the Provincial Government of Gipuzkoa (DFG06/002, DFG08/001 and DFG15/221) and annual agreements with the municipalities of the study area (Zumarraga, Urretxu, Ordizia, Legazpi, Azkoitia y Azpeitia y Beasain).
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Entidades Colaboradoras:
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Trihalomethane and haloacetic acid concentrations in drinking water and their estimated intake during pregnancy in the INMA cohort (Guipúzcoa, Spain)
Santa Marina L, Ayerdi M, Lertxundi A, Basterretxea M, Goñi F, Iñaki Alvare J, Arranz L, Blarduni E, María Ibarluzea J. Trihalomethane and haloacetic acid concentrations in drinking water and their estimated intake during pregnancy in the INMA cohort (Guipúzcoa, Spain). Gac Sanit. 2010 Jul-Aug;24(4):321-8. Spanish. PMID: 20447740
Air quality assessment in urban areas of Gipuzkoa (Spain)
Lertxundi A, Martinez MD, Ayerdi M, Alvarez J, María Ibarluzea J. Air quality assessment in urban areas of Gipuzkoa (Spain). Gac Sanit. 2010 May-Jun;24(3):187-92. PMID: 20207046
Iodine intake and maternal thyroid function during pregnancy
Rebagliato M, Murcia M, Espada M, ‘Alvarez-Pedrerol M, Bolúmar F, Vioque J, Basterrechea M, Blarduni E, Ramón R, Guxens M, Foradada CM, Ballester F, Ibarluzea J, Sunyer J. Iodine intake and maternal thyroid function during pregnancy. Epidemiology.2010 Jan;21(1):62-9. PMID: 19940773
Organochlorine Compounds, Iodine Intake, and Thyroid Hormone Levels during Pregnancy
Alvarez-Pedrerol M, Guxens M, Ibarluzea J, Rebagliato M, Rodriguez A, Espada M, Goñi F, Basterrechea M, Sunyer J. Organochlorine Compounds, Iodine Intake, and Thyroid Hormone Levels during Pregnancy. Environ Sci Technol. 2009 Oct 15;43(20):7909-7915. PMID: 19921913
The Spanish Environment and Childhood Research Network (INMA study)
Fernandez MF, Sunyer J, Grimalt J, Rebagliato M, Ballester F, Ibarluzea J, Ribas-Fitó N, Tardon A, Fernandez-Patier R, Torrent M, Olea N. The Spanish Environment and Childhood Research Network (INMA study). Int J Hyg Environ Health. 2007;210(3-4):491-3. Epub 2007 Feb 22. PMID: 17320477
Air pollutant exposure during pregnancy and fetal and early childhood development. Research protocol of the INMA (Childhood and Environment Project)
Esplugues A, Fernández-Patier R, Aguilera I, Iñíguez C, García Dos Santos S, Aguirre Alfaro A, Lacasaña M, Estarlich M, Grimalt JO, Fernández M, Rebagliato M, Sala M, Tardón A, Torrent M, Martínez MD, Ribas-Fitó N, Sunyer J, Ballester F. Air pollutant exposure during pregnancy and fetal and early childhood development. Research protocol of the INMA (Childhood and Environment Project). Gac Sanit. 2007;21(2):162-71. Spanish. PMID: 17419934
Efectos de la exposición prenatal a contaminantes ambientales y de la dieta materna en el neurodesarrollo. La Red de investigación ‘Infancia y Medio Ambiente’ (Red INMA)
Rebagliato M, Ballester F, Ramon RM, Marco A. The effects of prenatal exposure to environmental pollutants and the mother’s diet on neurodevelopment. The ‘Infancy and Environment’ Research Network (INMA Network). Rev Neurol. 2007 21;44 Suppl 3:S15-8. Spanish. PMID: 17523104
Measurement of drinking water contaminants and water use activities during pregnancy in a cohort study in Spain
Villanueva CM, Grimalt JO, Ballester F, Ibarluzea J, Sala M, Tardón A, Romero-Aliaga E, Fernández M, Ribas-Fitó N, Kogevinas M. Measurement of drinking water contaminants and water use activities during pregnancy in a cohort study in Spain. Gac Sanit. 2006;20 Suppl 3:1-9. Spanish. PMID: 17433195
Child health and the environment: the INMA Spanish Study
Ribas-Fitó N, Ramón R, Ballester F, Grimalt J, Marco A, Olea N, Posada M, Rebagliato M, Tardón A, Torrent M, Sunyer J. Child health and the environment: the INMA Spanish Study. Paediatr Perinat Epidemiol. 2006;20(5):403-10. PMID: 16911019
The Environment and Childhood Research Network (“INMA” network): study protocol
Ramón R, Ballester F, Rebagliato M, Ribas N, Torrent M, Fernández M, Sala M, Tardón A, Marco A, Posada M, Grimalt J, Sunyer J; Red INMA. The Environment and Childhood Research Network (“INMA” network): study protocol.Rev Esp Salud Publica. 2005 Mar-Apr;79(2):203-20. Spanish. PMID: 15913055
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