Gipuzkoa
2006ko maiatzean, “Haurtzaroa eta Ingurumena” (INMA) proiektua jarri zen martxan Gipuzkoan. Helburu nagusia zen airean, uretan eta dietan aurkitzen diren ingurumen-kutsatzaileek haurren hazkuntzan etagarapenean izan dezaketen eragina aztertzea. Emakumeak haurdunaldiko kontrolaren lehen ekografia egitean sartzen dira kohortean.Lagin biologikoak (odola, gernua, ilea, plazenta, eta abar) jasotzeaz gain, zenbait galdesorta (orokorra, dietaz, lanaz, ingurugiroaz, eta abar) betetzen dira, batetik, airean, ingurugiroan eta kontsumoko uretan aurkitzen diren kutsatzaileen balorazioa egiteko, eta, bestetik, dieta bidez jasotako kutsatzaileen estimazioa ateratzeko.
Zumarragako Ospitaleari dagokion biztanleriak definitzen du ikerketaren inguru geografikoa, hau da, Goierriko eta Urola Garaiko nahiz Urola Erdiko udalerriak. Inguru hori aukeratu zen, hain zuen, lehen mailako arreta eskaintzeagatik eta ospitaleko zerbitzuen ezaugarriengatik, eta baita ingurumen ezaugarriengatik ere: industria siderometalurgiko ugaria, zirkulazio-dentsitate altua, desinfektatzetik eratorritako produktuen maila baxua edateko uretan, arrain ugariko dieta, eta, horiekin batera, hipotiroidismo pixka bat emakume haurdunengan.
Orduz geroztik, 640 emakumeren jarraipena egin da haurdunaldiaren lehenengo eta hirugarren hilabeteetan. Gaur egun, 623 haurren jarraipena egiten ari gara hazkuntzaren eta garapen neurokonduktualaren gainean.
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Financiadores de la cohorte INMA-Gipuzkoa:
This study was funded by grants from Instituto de Salud Carlos III (FIS-PI06/0867, FIS-PI09/00090, FIS-PI13/02187 and FIS-PI18/01142 incl. FEDER funds), CIBERESP, Department of Health of the Basque Government (2005111093, 2009111069, 2013111089 and 2015111065), and the Provincial Government of Gipuzkoa (DFG06/002, DFG08/001 and DFG15/221) and annual agreements with the municipalities of the study area (Zumarraga, Urretxu, Ordizia, Legazpi, Azkoitia y Azpeitia y Beasain).
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Entidades Colaboradoras:
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Comparison of urinary iodine levels in women of childbearing age during and after pregnancy
Castilla AM, Murcia M, Arrizabalaga JJ, Espada M, Julvez J, Basterrechea M, Alvarez-Pedrerol M, Estarlich M, Moreno E, Guxens M, Vioque J, Rebagliato M. Comparison of urinary iodine levels in women of childbearing age during and after pregnancy. Eur J Nutr. 2018 Aug;57(5):1807-1816. PMID: 28456846
Fluoride intake through consumption of water from municipal network in the INMA-Gipuzkoa cohort
Jiménez-Zabala A, Santa-Marina L, Otazua M, Ayerdi M, Galarza A, Gallastegi M, Ulibarrena E, Molinuevo A, Anabitarte A, Ibarluzea J. [Fluoride intake through consumption of water from municipal network in the INMA-Gipuzkoa cohort]. Gac Sanit. 2018 Sep – Oct;32(5):418-424. PMID: 28545738
Air pollution exposure during pregnancy and symptoms of attention deficit and hyperactivity disorder in children in Europe
Forns J, Sunyer J, Garcia-Esteban R, Porta D, Ghassabian A, Giorgis-Allemand L, Gong T, Gehring U, Sørensen M, Standl M, Sugiri D, Almqvist C, Andiarena A, Badaloní C, Beelen R, Berdel D, Cesaroni G, Charles MA, Eriksen KT, Estarlich M, Fernandez MF, Forhan A, Jaddoe VWV, Korek M, Lichtenstein P, Lertxundi A, Lopez-Espinosa MJ, Markevych I, de Nazelle A, Raaschou-Nielsen O, Nieuwenhuijsen M, Pérez-Lobato R, Philippat C, Slama R, Tiesler CM, Verhulst FC, von Berg A, Vrijkotte T, Nybo Andersen AM, Heude B, Krämer U, Heinrich J, Tiemeier H, Forastiere F, Pershagen G, Brunekreef B, Guxens M. Air pollution exposure during pregnancy and symptoms of attention deficit and hyperactivity disorder in children in Europe. Epidemiology. 2018 Sep;29(5):618-626. PMID: 29923866
Thyroid Function in Early Pregnancy, Child IQ, and Autistic Traits: a Meta-analysis of Individual-participant Data
Levie D, Korevaar TIM, Bath SC, Dalmau-Bueno A, Murcia M, Espada M, Dineva M, Ibarluzea JM, Sunyer J, Tiemeier H, Rebagliato M, Rayman MP, Peeters RP, Guxens M. Thyroid Function in Early Pregnancy, Child IQ, and Autistic Traits: a Meta-analysis of Individual-participant Data. J Clin Endocrinol Metab. 2018 Aug 1;103(8):2967-2979. PMID: 29757392
Prenatal and postnatal exposure to persistent organic pollutants (POPs) and attention-deficit and hyperactivity disorder (ADHD): a pooled analysis of seven European birth cohort studies
Forns J, Stigum H, Høyer BB, Sioen I, Sovcikova E, Nowack N, Lopez-Espinosa MJ, Guxens M, Ibarluzea J, Torrent M, Wittsiepe J, Govarts E, Trnovec T, Chevrier C, Toft G, Vrijheid M, Iszatt N, Eggesbø M. Prenatal and postnatal exposure to persistent organic pollutants (POPs) and attention-deficit and hyperactivity disorder (ADHD): a pooled analysis of seven European birth cohort studies. Int J Epidemiol. 2018 Aug 1;47(4):1082-1097. PMID: 29912347
Influence of maternal obesity on the association between common pregnancy complications and risk of childhood obesity: an individual participant data meta-analysis
Patro Golab B, Santos S, Voerman E, Lawlor DA, Jaddoe VWV, Gaillard R; MOCO Study Group Authors. Influence of maternal obesity on the association between common pregnancy complications and risk of childhood obesity: an individual participant data meta-analysis. Lancet Child Adolesc Health. 2018 Nov;2(11):812-821. PMID: 30201470
Urine Metabolic Signatures of Multiple Environmental Pollutants in Pregnant Women: An Exposome Approach
Maitre L, Robinson O, Martinez D, Toledano MB, Ibarluzea J, Marina LS, Sunyer J, Villanueva CM, Keun HC, Vrijheid M, Coen M. Urine Metabolic Signatures of Multiple Environmental Pollutants in Pregnant Women: An Exposome Approach. Environ Sci Technol. 2018 Nov 20;52(22):13469-13480. PMID: 30285427
Maternal cell phone use during pregnancy and child cognition at age 5 years in 3 birth cohorts
Sudan M, Birks LE, Aurrekoetxea JJ, Ferrero A, Gallastegi M, Guxens M, Ha M, Lim H, Olsen J, González-Safont L, Vrijheid M, Kheifets L. Maternal cell phone use during pregnancy and child cognition at age 5 years in 3 birth cohorts. Environ Int. 2018 Nov;120:155-162. PMID: 30096609
Personal exposure to radio-frequency electromagnetic fields in Europe: Is there a generation gap?
Eeftens M, Struchen B, Birks LE, Cardis E, Estarlich M, Fernandez MF, Gajšek P, Gallastegi M, Huss A, Kheifets L, Meder IK, Olsen J, Torrent M, Trček T, Valič B, Vermeulen R, Vrijheid M, van Wel L, Guxens M, Röösli M. Personal exposure to radio-frequency electromagnetic fields in Europe: Is there a generation gap?. Environ Int. 2018 Dec;121(Pt 1):216-226. PMID: 30216774
The INMA-INfancia y Medio Ambiente-(Environment and Childhood) project: More than 10 years contributing to environmental and neuropsychological research
Gascon M, Guxens M, Vrijheid M, Torrent M, Ibarluzea J, Fano E, Llop S, Ballester F, Fernández MF, Tardón A, Fernández-Somoano A, Sunyer J. The INMA-INfancia y Medio Ambiente-(Environment and Childhood) project: More than 10 years contributing to environmental and neuropsychological research. Int J Hyg Environ Health. 2017 Jun;220(4):647-658. PMID: 28291591
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