Resultados del estudio
A meta-analysis of pre-pregnancy maternal body mass index and placental DNA methylation identifies 27 CpG sites with implications for mother-child health
Fernandez-Jimenez N, Fore R, Cilleros-Portet A, Lepeule J, Perron P, Kvist T, Tian FY, Lesseur C, Binder AM, Lozano M, Martorell-Marugán J, Loke YJ, Bakulski KM, Zhu Y, Forhan A, Sammallahti S, Everson TM, Chen J, Michels KB, Belmonte T, Carmona-Sáez P, Halliday J, Daniele Fallin M, LaSalle JM, Tost J, Czamara D, Fernández MF, Gómez-Martín A, Craig JM, Gonzalez-Alzaga B, Schmidt RJ, Dou JF, Muggli E, Lacasaña M, Vrijheid M, Marsit CJ, Karagas MR, Räikkönen K, Bouchard L, Heude B, Santa-Marina L, Bustamante M, Hivert MF, Bilbao JR. A meta-analysis of pre-pregnancy maternal body mass index and placental DNA methylation identifies 27 CpG sites with implications for mother-child health. Commun Biol. 2022 Nov 30;5(1):1313. PMID: 36446949
Exposure to natural environments during pregnancy and birth outcomes in 11 European birth cohorts
Torres Toda M, Avraam D, James Cadman T, Fossati S, de Castro M, Dedele A, Donovan G, Elhakeem A, Estarlich M, Fernandes A, Gonçalves R, Grazuleviciene R, Harris JR, Harskamp-van Ginkel MW, Heude B, Ibarluzea J, Iñiguez C, Wv Jaddoe V, Lawlor D, Lertxundi A, Lepeule J, McEachan R, Moirano G, Lt Nader J, Nybo Andersen AM, Pedersen M, Pizzi C, Roumeliotaki T, Santos S, Sunyer J, Yang T, Vafeiadi M, Gm Vrijkotte T, Nieuwenhuijsen M, Vrijheid M, Foraster M, Dadvand P. Exposure to natural environments during pregnancy and birth outcomes in 11 European birth cohorts. Environ Int. 2022 Dec;170:107648. PMID: 36436464
The association between maternal ultra-processed food consumption during pregnancy and child neuropsychological development: A population-based birth cohort study
Puig-Vallverdú J, Romaguera D, Fernández-Barrés S, Gignac F, Ibarluzea J, Santa-Maria L, Llop S, Gonzalez S, Vioque J, Riaño-Galán I, Fernández-Tardón G, Pinar A, Turner MC, Arija V, Salas-Savadó J, Vrijheid M, Julvez J. The association between maternal ultra-processed food consumption during pregnancy and child neuropsychological development: A population-based birth cohort study. Clin Nutr. 2022 Oct;41(10):2275-2283. PMID: 36087519
Multi-omics signatures of the human early life exposome
Maitre L, Bustamante M, Hernández-Ferrer C, Thiel D, Lau CE, Siskos AP, Vives-Usano M, Ruiz-Arenas C, Pelegrí-Sisó D, Robinson O, Mason D, Wright J, Cadiou S, Slama R, Heude B, Casas M, Sunyer J, Papadopoulou EZ, Gutzkow KB, Andrusaityte S, Grazuleviciene R, Vafeiadi M, Chatzi L, Sakhi AK, Thomsen C, Tamayo I, Nieuwenhuijsen M, Urquiza J, Borràs E, Sabidó E, Quintela I, Carracedo Á, Estivill X, Coen M, González JR, Keun HC, Vrijheid M. Multi-omics signatures of the human early life exposome. Nat Commun. 2022 Nov 21;13(1):7024. PMID: 36411288
Genome-wide distribution of histone trimethylation reveals a global impact of bisphenol A on telomeric binding proteins and histone acetyltransferase factors: a pilot study with human and in vitro data
D’Cruz SC, Hao C, Labussiere M, Mustieles V, Freire C, Legoff L, Magnaghi-Jaulin L, Olivas-Martinez A, Rodriguez-Carrillo A, Jaulin C, David A, Fernandez MF, Smagulova F. Genome-wide distribution of histone trimethylation reveals a global impact of bisphenol A on telomeric binding proteins and histone acetyltransferase factors: a pilot study with human and in vitro data. Clin Epigenetics. 2022 Dec 26;14(1):186. PMID: 36572933
Validation of a Parent-Reported Physical Activity Questionnaire by Accelerometry in European Children Aged from 6 to 12 Years Old
Prieto-Botella D, Valera-Gran D, Santa-Marina L, Babarro I, Subiza-Pérez M, Casas M, Guxens M, Cárdenas-Fuentes G, Heude B, Bernard JY, McEachan RRC, García-Aymerich J, Vrijheid M, Navarrete-Muñoz EM. Validation of a Parent-Reported Physical Activity Questionnaire by Accelerometry in European Children Aged from 6 to 12 Years Old. Int J Environ Res Public Health. 2022 Jul 27;19(15):9178. PMID: 35954544
Prenatal exposure to mixtures of phthalates and phenols and body mass index and blood pressure in Spanish preadolescents
Güil-Oumrait N, Cano-Sancho G, Montazeri P, Stratakis N, Warembourg C, Lopez-Espinosa MJ, Vioque J, Santa-Marina L, Jimeno-Romero A, Ventura R, Monfort N, Vrijheid M, Casas M. Prenatal exposure to mixtures of phthalates and phenols and body mass index and blood pressure in Spanish preadolescents. Environ Int. 2022 Nov;169:107527. PMID: 36126421
Identification of autosomal cis expression quantitative trait methylation (cis eQTMs) in children’s blood
Ruiz-Arenas C, Hernandez-Ferrer C, Vives-Usano M, Marí S, Quintela I, Mason D, Cadiou S, Casas M, Andrusaityte S, Gutzkow KB, Vafeiadi M, Wright J, Lepeule J, Grazuleviciene R, Chatzi L, Carracedo Á, Estivill X, Marti E, Escaramís G, Vrijheid M, González JR, Bustamante M. Identification of autosomal cis expression quantitative trait methylation (cis eQTMs) in children’s blood. Elife. 2022 Mar 18;11:e65310. PMID: 35302492
Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation
Solomon O, Huen K, Yousefi P, Küpers LK, González JR, Suderman M, Reese SE, Page CM, Gruzieva O, Rzehak P, Gao L, Bakulski KM, Novoloaca A, Allard C, Pappa I, Llambrich M, Vives M, Jima DD, Kvist T, Baccarelli A, White C, Rezwan FI, Sharp GC, Tindula G, Bergström A, Grote V, Dou JF, Isaevska E, Magnus MC, Corpeleijn E, Perron P, Jaddoe VWV, Nohr EA, Maitre L, Foraster M, Hoyo C, Håberg SE, Lahti J, DeMeo DL, Zhang H, Karmaus W, Kull I, Koletzko B, Feinberg JI, Gagliardi L, Bouchard L, Ramlau-Hansen CH, Tiemeier H, Santorelli G, Maguire RL, Czamara D, Litonjua AA, Langhendries JP, Plusquin M, Lepeule J, Binder EB, Verduci E, Dwyer T, Carracedo Á, Ferre N, Eskenazi B, Kogevinas M, Nawrot TS, Munthe-Kaas MC, Herceg Z, Relton C, Melén E, Gruszfeld D, Breton C, Fallin MD, Ghantous A, Nystad W, Heude B, Snieder H, Hivert MF, Felix JF, Sørensen TIA, Bustamante M, Murphy SK, Raikkönen K, Oken E, Holloway JW, Arshad SH, London SJ, Holland N. Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation. Mutat Res Rev Mutat Res. 2022 Jan-Jun;789:108415. PMID: 35690418
Environmental and dietary determinants of metal exposure in four-year-old children from a cohort located in an industrial area (Asturias, Northern Spain)
Junqué E, Tardón A, Fernandez-Somoano A, Grimalt JO. Environmental and dietary determinants of metal exposure in four-year-old children from a cohort located in an industrial area (Asturias, Northern Spain). Environ Res. 2022 Nov;214(Pt 2):113862. PMID: 35850295
Serum concentrations of persistent organic pollutants mixture during pregnancy and anogenital distance in 8-year-old children from the INMA-Asturias cohort
García-Villarino M, Signes-Pastor AJ, Riaño-Galán I, Rodríguez-Dehli AC, Vizcaíno E, Grimalt JO, Fernández-Somoano A, Tardón A. Serum concentrations of persistent organic pollutants mixture during pregnancy and anogenital distance in 8-year-old children from the INMA-Asturias cohort. Environ Res. 2022 Oct;213:113607. PMID: 35690090
Do prepubertal hormones, 2D:4D index and psychosocial context jointly explain 11-year-old preadolescents’ involvement in bullying?
Babarro I, Andiarena A, Fano E, García-Baquero G, Lebeña A, Arranz-Freijo EB, Ibarluzea J. Do prepubertal hormones, 2D:4D index and psychosocial context jointly explain 11-year-old preadolescents’ involvement in bullying? Biol Psychol. 2022 Jul;172:108379. PMID: 35690279
Pre and postnatal exposure to mercury and sexual development in 9-year-old children in Spain: The role of brain-derived neurotrophic factor
Sarzo B, Ballester F, Soler-Blasco R, Lopez-Espinosa MJ, Lozano M, Iriarte G, Beneito A, Riutort-Mayol G, Murcia M, Llop S. Pre and postnatal exposure to mercury and sexual development in 9-year-old children in Spain: The role of brain-derived neurotrophic factor. Environ Res. 2022 Oct;213:113620. PMID: 35697081
Maternal Dietary Glycemic Index and Glycemic Load in Pregnancy and Offspring Cord Blood DNA Methylation
Küpers LK, Fernández-Barrés S, Mancano G, Johnson L, Ott R, Vioque J, Colombo M, Landgraf K, Tobi EW, Körner A, Gaillard R, de Vries JHM, Jaddoe VWV, Vrijheid M, Sharp GC, Felix JF. Maternal Dietary Glycemic Index and Glycemic Load in Pregnancy and Offspring Cord Blood DNA Methylation. Diabetes Care. 2022 Aug 1;45(8):1822-1832. PMID: 35708509
Genetics of early-life head circumference and genetic correlations with neurological, psychiatric and cognitive outcomes
Vogelezang S, Bradfield JP; Early Growth Genetics Consortium, Grant SFA, Felix JF, Jaddoe VWV. Genetics of early-life head circumference and genetic correlations with neurological, psychiatric and cognitive outcomes. BMC Med Genomics. 2022 Jun 4;15(1):124. PMID: 35659227
The early-life exposome modulates the effect of polymorphic inversions on DNA methylation
Carreras-Gallo N, Cáceres A, Balagué-Dobón L, Ruiz-Arenas C, Andrusaityte S, Carracedo Á, Casas M, Chatzi L, Grazuleviciene R, Gutzkow KB, Lepeule J, Maitre L, Nieuwenhuijsen M, Slama R, Stratakis N, Thomsen C, Urquiza J, Wright J, Yang T, Escaramís G, Bustamante M, Vrijheid M, Pérez-Jurado LA, González JR. The early-life exposome modulates the effect of polymorphic inversions on DNA methylation. Commun Biol. 2022 May 12;5(1):455. PMID: 35550596
Urban environment and health behaviours in children from six European countries
Fernández-Barrés S, Robinson O, Fossati S, Márquez S, Basagaña X, de Bont J, de Castro M, Donaire-Gonzalez D, Maitre L, Nieuwenhuijsen M, Romaguera D, Urquiza J, Chatzi L, Iakovides M, Vafeiadi M, Grazuleviciene R, Dedele A, Andrusaityte S, Marit Aasvang G, Evandt J, Hjertager Krog N, Lepeule J, Heude B, Wright J, McEachan RRC, Sassi F, Vineis P, Vrijheid M. Urban environment and health behaviours in children from six European countries. Environ Int. 2022 Jul;165:107319. PMID: 35667344
Longitudinal associations of DNA methylation and sleep in children: a meta-analysis
Sammallahti S, Koopman-Verhoeff ME, Binter AC, Mulder RH, Cabré-Riera A, Kvist T, Malmberg ALK, Pesce G, Plancoulaine S, Heiss JA, Rifas-Shiman SL, Röder SW, Starling AP, Wilson R, Guerlich K, Haftorn KL, Page CM, Luik AI, Tiemeier H, Felix JF, Raikkonen K, Lahti J, Relton CL, Sharp GC, Waldenberger M, Grote V, Heude B, Annesi-Maesano I, Hivert MF, Zenclussen AC, Herberth G, Dabelea D, Grazuleviciene R, Vafeiadi M, Håberg SE, London SJ, Guxens M, Richmond RC, Cecil CAM. Longitudinal associations of DNA methylation and sleep in children: a meta-analysis. Clin Epigenetics. 2022 Jul 5;14(1):83. PMID: 35790973
Study of the Combined Effect of Maternal Tobacco Smoking and Polygenic Risk Scores on Birth Weight and Body Mass Index in Childhood
Fuentes-Paez G, Escaramís G, Aguilar-Lacasaña S, Andrusaityte S, Brantsæter AL, Casas M, Charles MA, Chatzi L, Lepeule J, Grazuleviciene R, Gützkow KB, Heude B, Maitre L, Ruiz-Arenas C, Sunyer J, Urquiza J, Yang TC, Wright J, Vrijheid M, Vilor-Tejedor N, Bustamante M. Study of the Combined Effect of Maternal Tobacco Smoking and Polygenic Risk Scores on Birth Weight and Body Mass Index in Childhood. Front Genet. 2022 May 12;13:867611. PMID: 35646076
Maternal occupational exposure to chemicals and child cognitive function
Ish J, Symanski E, Gimeno Ruiz de Porras D, Casas M, Delclos GL, Guxens M, Ibarluzea JM, Iñiguez C, Lertxundi A, Rebagliato M, Swartz MD, Whitworth KW. Maternal occupational exposure to chemicals and child cognitive function. Pediatr Res. 2022 Oct;92(4):1153-1160. PMID: 35578010
Correction: Maternal occupational exposure to chemicals and child cognitive function. Pediatr Res. 2023 Jan;93(1):278-279. PMID: 36138064
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