Resultados del estudio

835 Resultados

Alteraciones hormonales -
Compuestos tóxicos no persistentes -
Compuestos tóxicos persistentes -
Marcadores-biomarcadores -


Unmasking metabolic disruptors: The NEMESIS project’s quest for Novel Biomarkers, Evidence on Adverse Effects, and Efficient Methodologies

Hakomäki H, Pitkänen S, Levonen AL, Honkakoski P, Greco D, D’Alessandro N, Saarimäki LA, Viegas S, Godinho C, Fyhrquist N, Wincent E, Lauschke VM, Hukkanen J, Hakkola J, Vallier L, Fortino V, Afantitis A, Sawatani T, Guzman TJ, Cnop M, Nawrot T, Harlid S, Vinnars MT, Tardon A, Grimalt JO, Küblbeck J, Rysä J. Unmasking metabolic disruptors: The NEMESIS project’s quest for Novel Biomarkers, Evidence on Adverse Effects, and Efficient Methodologies. Open Res Eur. 2025 Dec 9;4:194. PMID: 41477515


Compuestos tóxicos no persistentes -
Compuestos tóxicos persistentes -
Marcadores-biomarcadores -


Methodological approach for a simultaneous determination of persistent and non-persistent organic pollutants in human blood (serum/plasma) using gas chromatography and mass spectrometry techniques

Bustamante CM, Ruiz P, Rifat AB, Bravo N, Grimalt JO, Garí M. Methodological approach for a simultaneous determination of persistent and non-persistent organic pollutants in human blood (serum/plasma) using gas chromatography and mass spectrometry techniques. J Chromatogr A. 2025 Sep 27;1759:466235. PMID: 40743678


Contaminación del aire -
Epigenética -


Road traffic noise exposure and blood DNA methylation at birth and in childhood: An epigenome-wide meta-analysis

Yu Z, Fontes Marques I, Kebede Merid S, Burrows K, Soares AG, Pyko A, Ögren M, Pershagen G, Lepeule J, Hjertager Krog N, Aasvang GM, Kusters MSW, Foraster M, Bustamante M, Leskien M, Thiering E, Elhakeem A, Peters A, Koppelman GH, Gehring U, Vonk JM, Jeong A, Imboden M, Probst-Hensch N, Vermeulen R, Nieuwenhuijsen M, Guxens M, Standl M, Jaddoe VWJ, London SJ, Melén E, Felix JF, Gruzieva O. Road traffic noise exposure and blood DNA methylation at birth and in childhood: An epigenome-wide meta-analysis. Environ Int. 2026 Jan;207:109976. PMID: 41352164


Cardiometabólico -
Crecimiento postnatal y Obesidad -


Determinants of overweight and obesity and other cardiometabolic risks in adolescents: a Spanish longitudinal birth study

Lozano M, Vallejo-Ortega J, Marín N, González-Safont L, Esplugues A, Lopez-Espinosa MJ, Beneito A, González-Palacios S, Llop S, Soler-Blasco R. Determinants of overweight and obesity and other cardiometabolic risks in adolescents: a Spanish longitudinal birth study. Pediatr Res. 2025 Dec;98(6):2087-2100. PMID: 40681697


Genética -


Saliva as a potential diagnostic medium: DNA methylation biomarkers for disorders beyond the oral cavity

Hernangomez-Laderas A, Cilleros-Portet A, Marí S, González-García BP, Arregi A, Jimeno-Romero A, Irizar A, García-Santisteban I, Lesseur C, Fernandez-Jimenez N, Bilbao JR. Saliva as a potential diagnostic medium: DNA methylation biomarkers for disorders beyond the oral cavity. NPJ Genom Med. 2025 Jun 20;10(1):49. PMID: 40541940


Compuestos tóxicos persistentes -


Tracking early-life PFAS exposure in children at ages 4, 8, and 14 years: A longitudinal study from the INMA Spanish birth cohort

San Román A, Abilleira E, González-Gaya B, Ayala-Cabrera JF, Barroeta Z, Etxebarria N, Irizar A. Tracking early-life PFAS exposure in children at ages 4, 8, and 14 years: A longitudinal study from the INMA Spanish birth cohort. Environ Res. 2025 Oct 15;283:122198. PMID: 40543869.


Nutrición -


The Association Between the Mediterranean Diet and Fatty Acids in Red Blood Cells of Spanish Adolescents

Ayala-Aldana N, Lafuente D, Lázaro I, Pinar-Martí A, Manidis A, Bernardo-Castro S, Fernandez-Barres S, Healy DR, Vrijheid M, Contreras-Rodríguez O, Sala-Vila A, Julvez J. The Association Between the Mediterranean Diet and Fatty Acids in Red Blood Cells of Spanish Adolescents. Nutrients. 2025 Sep 6;17(17):2888. PMID: 40944276


Neurodesarrollo -
Nutrición -


Red Blood Cell Fatty Acid Patterns and Cognitive Functions in Adolescents: A Pooled Analyses with Two Cohort Study Data Sets

Ayala-Aldana N, Pinar-Martí A, Ruiz-Rivera M, Lázaro I, Sala-Vila A, Healy DR, Contreras-Rodriguez O, Casanova J, Sola-Valls N, Vrijheid M, Julvez J. Red Blood Cell Fatty Acid Patterns and Cognitive Functions in Adolescents: A Pooled Analyses with Two Cohort Study Data Sets. Nutrients. 2025 Nov 5;17(21):3483. PMID: 41228554


Genética -
Salud respiratoria y atopia -


Gene-Environment Interaction Affects Risk of Atopic Eczema: Population and In Vitro Studies

Standl M, Budu-Aggrey A, Johnston LJ, Elias MS, Arshad SH, Bager P, Bataille V, Blakeway H, Bønnelykke K, Boomsma D, Brumpton BM, Bustamante Pineda M, Campbell A, Curtin JA, Eliasen A, Fadista JPS, Feenstra B, Gerner T, Medina-Gomez C, Grosche S, Gutzkow KB, Halling AS, Hayward C, Henderson J, Herrera-Luis E, Holloway JW, Hottenga J, O’B Hourihane J, Hu C, Hveem K, Irizar A, Jacquemin B, Jessen L, Kress S, Kurukulaaratchy RJ, Lau S, Llop S, Løset M, Marenholz I, Mason D, McCartney DL, Melbye M, Melén E, Minica C, Murray CS, Nijsten T, Pardo LM, Pasmans S, Pennell CE, Rinnov MR, Santorelli G, Schikowski T, Sheehan D, Simpson A, Söderhäll C, Thomas LF, Thyssen JP, Torrent M, van Beijsterveldt T, Visconti A, Vonk JM, Wang CA, Xu CJ, Ziyab AH; UK Translational Research Network in Dermatology; BIOMAP Consortium; Custovic A, Di Meglio P, Duijts L, Flohr C, Irvine AD, Koppelman GH, Lee YA, Reynolds NJ, Smith C, Langan SM, Paternoster L, Brown SJ. Gene-Environment Interaction Affects Risk of Atopic Eczema: Population and In Vitro Studies. Allergy. 2025 Aug;80(8):2201-2212. PMID: 40462597. Erratum in: Allergy. 2026 Feb;81(2):626. PMID: 40958161 .


Alteraciones hormonales -
Salud reproductiva -


Association of gestational thyroid function and thyroid autoimmunity with gestational diabetes: a systematic review and individual participant meta-analysis

Osinga JAJ, Derakhshan A, Karachaliou M, Poppe KG, Warringa L, Verdonk K, Vaidya B, Männistö T, López-Bermejo A, Bassols J, Broeren MAC, Brown SJ, Jensen RC, Popova PV, Pop VJM, Feldt-Rasmussen U, Aminorroaya A, Bliddal S, Mosso L, Chatzi L, Boucai L, Itoh S, Kishi R, Kleynen P, Ashoor G, Oken E, Grineva EN, Lu X, Lertxundi A, Murcia M, Meertens-Gunput STG, Rebagliato M, Riaño-Galán I, Irizar A, Vrijheid M, Fernández-Somoano A, Suvanto E, Guxens M, Daraki V, Mathieu C, Kianpour M, Glintborg D, Jensen TK, Alexander E, Chaker L, Malone F, Messerlian G, Hattersley A, Harley KG, Pearce EN, Visser WE, Vrijkotte TGM, Peeters RP, Palomaki GE, Lowe W, Eskenazi B, Chen LM, Walsh JP, Nicolaides KH, Carty DM, Delles C, Tao FB, Huang K, Maraka S, D’Alton ME, Painter RC, Andersen MS, Benhalima K, Korevaar TIM. Association of gestational thyroid function and thyroid autoimmunity with gestational diabetes: a systematic review and individual participant meta-analysis. Lancet Diabetes Endocrinol. 2025 Aug;13(8):651-661. PMID: 40609565


Neurodesarrollo -


Early nursery attendance and infant neurodevelopment at 1 year of age

L. González-Safont, P. Carrasco, R. Abumallouh, S. Llop, M. Estarlich & M. Rebagliato. Early nursery attendance and infant neurodevelopment at 1 year of age. Early Child Development and Care 2025, 195:7-8, 744-760
Link to this article: https://doi.org/10.1080/03004430.2025.2528843


Genética -
Neurodesarrollo -


Genome-wide association meta-analysis of childhood ADHD symptoms and diagnosis identifies new loci and potential effector genes

van der Laan CM, Ip HF, Schipper M, Hottenga JJ, St Pourcain B, Zayats T, Pool R, Krapohl EML, Brikell I, Soler Artigas M, Cabana-Domínguez J, Llonga N, Nolte IM, Bolhuis K, Palviainen T, Zafarmand H, Gordon S, Aliev F, Burt SA, Wang CA, Saunders G, Karhunen V, Adkins DE, Border R, Peterson RE, Prinz JA, Thiering E, Vilor-Tejedor N, Ahluwalia TS, Allegrini A, Rimfeld K, Chen Q, Lu Y, Martin J, Bosch R, Ramos-Quiroga JA, Neumann A, Ensink J, Grasby KL, Morosoli JJ, Tong X, Marrington S, Scott JG, Shabalin AA, Corley R, Evans LM, Sugden K, Alemany S, Sass L, Vinding R, Ehli EA, Hagenbeek FA, Derks EM, Larsson H, Snieder H, Cecil C, Whipp AM, Korhonen T, Vuoksimaa E, Rose RJ, Uitterlinden AG, Haavik J, Harris JR, Helgeland Ø, Johansson S, Knudsen GPS, Njolstad PR, Lu Q, Rodriguez A, Henders AK, Mamun A, Najman JM, Brown S, Hopfer C, Krauter K, Reynolds CA, Smolen A, Stallings M, Wadsworth S, Wall TL, Eaves L, Silberg JL, Miller A, Havdahl A, Llop S, Lopez-Espinosa MJ, Bønnelykke K, Sunyer J, Arseneault L, Standl M, Heinrich J, Boden J, Pearson J, Horwood J, Kennedy M, Poulton R, Maes HH, Hewitt J, Copeland WE, Middeldorp CM, Williams GM, Wray N, Järvelin MR, McGue M, Iacono W, Caspi A, Moffitt TE, Whitehouse AJO, Pennell CE, Klump KL, Jiang C, Dick DM, Reichborn-Kjennerud T, Martin NG, Medland SE, Vrijkotte T, Kaprio J, Tiemeier H, Davey Smith G, Hartman CA, Oldehinkel AJ, Casas M, Ribasés M, Lichtenstein P, Lundström S, Plomin R, Bartels M, Nivard MG, Boomsma DI. Genome-wide association meta-analysis of childhood ADHD symptoms and diagnosis identifies new loci and potential effector genes. Nat Genet. 2025 Oct;57(10):2427-2435. PMID: 40962958. Erratum in: Nat Genet. 2025 Oct;57(10):2604. PMID: 41023451.


Cardiometabólico -
Epigenética -
Metales -


Association of pre-and postnatal mercury exposure with cardiometabolic risk factors in children: the role of the telomere length and telomerase reverse transcriptase polymorphisms

Lozano M, Soler-Blasco R, Ballester F, Gutzkow KB, Brantsæter AL, Karachaliou M, Stephanou EG, Symvoulakis EK, Grazuleviciene R, Andrusaityte S, Dedele A, Yang TC, McEachan RRC, Wright J, Heude B, Yuan WL, Vrijheid M, Maitre L, Stratakis N, Thomsen C, Nawrot T, Broberg K, Llop S. Association of pre-and postnatal mercury exposure with cardiometabolic risk factors in children: the role of the telomere length and telomerase reverse transcriptase polymorphisms. Environ Int. 2025 Nov;205:109880. PMID: 41205373


Compuestos tóxicos no persistentes -
Neurodesarrollo -


Prenatal and childhood exposure to mixtures of environmental chemicals and adolescence attentional problems: a triangulation study

Fabbri L, Andrušaitytė S, Basagaña X, Bhopal S, Bustamante M, Cheung RW, Gražulevičienė R, Guxens M, Kadawathagedara M, Kampouri M, Maitre L, Marquez S, Montazeri P, Myridakis A, Slama R, Thomsen C, Vrijheid M. Prenatal and childhood exposure to mixtures of environmental chemicals and adolescence attentional problems: a triangulation study. Environ Int. 2025 Dec;206:109927. PMID: 41252940


Cardiometabólico -
Crecimiento postnatal y Obesidad -
Exposoma -
Neurodesarrollo -
Salud respiratoria y atopia -


Early-life exposome and health-related immune signatures in childhood

Amine I, Anguita-Ruiz A, Guillien A, Basagaña X, Bustamante M, Borràs E, Cirach M, Dedele A, Dobaño C, Garcia-Aymerich J, Granum B, Grazuleviciene R, González JR, Julvez J, Keun H, López-Vicente M, McEachan R, Moncunill G, Nieuwenhuijsen M, Sabidó E, Slama R, Tenenhaus A, Vafeiadi M, Wright J, Yang T, Yuan WL, Vrijheid M, Siroux V, Maitre L. Early-life exposome and health-related immune signatures in childhood. Environ Int. 2025 Aug;202:109668. PMID: 40651279


Epigenética -
Marcadores inflamación -
Marcadores-biomarcadores -


Biological sex impacts immune cell proportions and epigenetic profiles in the developing pediatric immune system

Edwards K, Merrill SM, Konwar C, Jude MS, Zhuang BC, Meijer M, Navarro-Delgado E, MacIsaac JL, Mandhane P, Simons E, Moraes TJ, Azad MB, Subbarao P, Bustamante M, Vrijheid M, Turvey S, Kobor MS. Biological sex impacts immune cell proportions and epigenetic profiles in the developing pediatric immune system. Commun Biol. 2025 Oct 9;8(1):1447. PMID: 41068453


Epigenética -
Salud respiratoria y atopia -


Maternal asthma and newborn DNA methylation

Pedersen CT, Hoang TT, Jin J, Starnawska A, Granell R, Elliott HR, Huels A, Zar HJ, Stein DJ, Zhang Y, Dekker HTD, Duijts L, Felix JF, Sangüesa J, Bustamante M, Casas M, Vrijheid M, Kadalayil L, Rezwan FI, Arshad H, Holloway JW, Röder S, Zenclussen AC, Herberth G, Staunstrup NH, Horsdal HT, Mill J, Hannon E; iPSYCH-MINERvA Group; Annesi-Maesano I, Pesce G, Baïz N, Heude B, Hosseinian-Mohazzab S, Breton CV, Harlid S, Harbs J, Domellof M, West C, Yeung E, Zeng X, Nystad W, Håberg SE, Magnus MC, Schendel D, London SJ, Bønnelykke K. Maternal asthma and newborn DNA methylation. Clin Epigenetics. 2025 May 10;17(1):79. PMID: 40349045


Epigenética -
Neurodesarrollo -


Epigenetic timing effects on child developmental outcomes: a longitudinal meta-regression of findings from the Pregnancy And Childhood Epigenetics Consortium

Neumann A, Sammallahti S, Cosin-Tomas M, Reese SE, Suderman M, Alemany S, Almqvist C, Andrusaityte S, Arshad SH, Bakermans-Kranenburg MJ, Beilin L, Breton C, Bustamante M, Czamara D, Dabelea D, Eng C, Eskenazi B, Fuemmeler BF, Gilliland FD, Grazuleviciene R, Håberg SE, Herberth G, Holland N, Hough A, Hu D, Huen K, Hüls A, Jarvelin MR, Jin J, Julvez J, Koletzko BV, Koppelman GH, Kull I, Lu X, Maitre L, Mason D, Melén E, Merid SK, Molloy PL, Mori TA, Mulder RH, Page CM, Richmond RC, Röder S, Ross JP, Schellhas L, Sebert S, Sheppard D, Snieder H, Starling AP, Stein DJ, Tindula G, van IJzendoorn MH, Vonk J, Walton E, Witonsky J, Xu CJ, Yang IV, Yousefi PD, Zar HJ, Zenclussen AC, Zhang H, Tiemeier H, London SJ, Felix JF, Cecil C. Epigenetic timing effects on child developmental outcomes: a longitudinal meta-regression of findings from the Pregnancy And Childhood Epigenetics Consortium. Genome Med. 2025 Apr 14;17(1):39. PMID: 40229801


Alteraciones hormonales -
Contaminación del aire -
Entorno urbano y Verdor -
Marcadores inflamación -
Ruido -


Outdoor air pollution, road traffic noise, and allostatic load in children aged 6-11 years: evidence from six European cohorts

Mou Y, Kusters MSW, Robinson O, Maitre L, McEachan RRC, Yuan WL, Hjertager Krog N, Andrušaitytė S, Bustamante M, de Castro Pascual M, Dedele A, Wright J, Grazuleviciene R, Aasvang GM, Lepeule J, Nieuwenhuijsen M, Tiemeier H, Vrijheid M, Thomson EM, Guxens M. Outdoor air pollution, road traffic noise, and allostatic load in children aged 6-11 years: evidence from six European cohorts. Eur J Epidemiol. 2025 May;40(5):537-548. PMID: 40366609


Genética -


Epistasis of ERAP1 With 4 Major Histocompatibility Complex Class I Alleles in Frontal Fibrosing Alopecia: A Genome-Wide Association Study Meta-Analysis

Rayinda T, Dand N, McSweeney SM, Christou E, Ung CY, Stefanato CM, Fenton DA, Harries M, Palamaras I, Tidman A, Holmes S, Koutalopoulou A, Ardern-Jones M, Kaur M, Papanikou S, Chasapi V, Vañó-Galvan S, Saceda-Corralo D, Melián-Olivera A, Azcarraga-Llobet C, Lobato-Berezo A, Bustamante M, Sunyer J, Starace MVR, Piraccini BM, Wiss IP, Senna MM, Singh R, Hillmann K, Kanti-Schmidt V, Blume-Peytavi U, McGrath JA, Simpson MA, Tziotzios C. Epistasis of ERAP1 With 4 Major Histocompatibility Complex Class I Alleles in Frontal Fibrosing Alopecia: A Genome-Wide Association Study Meta-Analysis. JAMA Dermatol. 2025 Mar 1;161(3):310-314. PMID: 39937552


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