Genetic characterization of preschool wheeze phenotypes

Fischer-Rasmussen K, Granell R, Eliasen AU, Kreiner E, Pedersen CT, Luo Y, Chawes B, Stokholm J, Malby Schoos AM, Kumar A, Nybo Andersen AM, Feenstra B, Geller F, Siroux V, Demenais F, Bouzigon E, Jaddoe V, van der Valk RJP, Duijts L, Sunyer J, Guxens M, Marinelli M, Bustamante M, Heinrich J, Standl M, Curtin J, Simpson A, Murray C, Jacobsson B, Myhre R, Pennell CE, Daley D, Ober C, Gern JE, Jackson D, Boomsma DI, Hottenga JJ, Abdellaoui A, Holloway JW, Collins S, Turner S, Arshad SH, Ullah A, Melén E, Henderson J, Bisgaard H, Pedersen AG, Custovic A, Vonk JM, Koppelman GH, Kabesch M, Bønnelykke K; Multidisciplinary Study to Identify the Genetic and Environmental Causes of Asthma in the European Community (GABRIEL) consortium; EArly Genetics and Lifecourse Epidemiology (EAGLE) consortium. Genetic characterization of preschool wheeze phenotypes. J Allergy Clin Immunol. 2025 Dec;156(6):1537-1546. PMID: 40769318

Understanding Social Inequalities in Childhood Asthma: Quantifying the Mediating Role of Modifiable Early-Life Risk Factors in Seven European Birth Cohorts

Pinot de Moira A, Aurup AV, Avraam D, Zugna D, Jensen AKG, Welten M, Cadman T, de Lauzon-Guillain B, Duijts L, Elhakeem A, Esplugues A, Garcia-Aymerich J, García-Baquero G, González Safont L, Harris JR, Iñiguez C, Jaddoe VWV, McEachan RRC, Nader JLT, Santa Marina L, Swertz MA, Tafflet M, Vrijheid M, Wright J, Yang TC, Taylor-Robinson D, Richiardi L, Nybo Andersen AM. Understanding Social Inequalities in Childhood Asthma: Quantifying the Mediating Role of Modifiable Early-Life Risk Factors in Seven European Birth Cohorts. J Allergy Clin Immunol Pract. 2025 Jun;13(6):1385-1396. PMID: 40314625

Association of environmental noise exposure with cortisol levels in children from eight European birth cohorts

Arregi A, Robinson O, Aasvang GM, Andrusaityte S, Dedele A, Evandt J, Garcia-Baquero G, Krog NH, Guxens M, Jaddoe VWV, Karachaliou M, Lertxundi A, Margetaki K, McEachan R, Nieuwenhuijsen M, Philippat C, Pozo OJ, Slama R, Subiza-Pérez M, van Rossum EFC, Vrijheid M, Wright J, Yang TC, Vegas O, Lertxundi N. Association of environmental noise exposure with cortisol levels in children from eight European birth cohorts. Environ Res. 2025 Jul 15;277:121541. PMID: 40203977

Particulate matter exposure during pregnancy and birth outcomes: exposure windows of susceptibility and socioeconomic inequalities

Guxens M, Botella N, Stafoggia M, Canto M, Petricola S, Valentín A, Lertxundi A, Fernández-Somoano A, Freire C, García-Altés A, Diez E, Marí-Dell’Olmo M, Iñiguez C, López MJ, Ramis R, Binter AC. Particulate matter exposure during pregnancy and birth outcomes: exposure windows of susceptibility and socioeconomic inequalities. Eur J Epidemiol. 2025 Sep;40(9):1105-1121. PMID: 40705228

Meet-in-the-middle meets multi-omics identifying molecular signatures of environmental drivers of childhood overweight

Wang C, Reimann B, Nawrot TS, Martens DS, Wright J, McEachan R, Lepeule J, Yuan W, Chatzi L, Vafeiadi M, Grazuleviciene R, Andrusaityte S, Robinson O, Sunyer J, Keun H, Lau CE, Siskos AP, Coen M, Borràs E, Sabidó E, González JR, Vives-Usano M, Estivill X, Carracedo A, Ruiz-Arenas C, Quintela I, Casas M, Nieuwenhuijsen M, Tamayo I, Gutzkow KB, Thomsen C, Sakhi AK, Bustamante M, Maitre L, Vrijheid M, Plusquin M, Alfano R. Meet-in-the-middle meets multi-omics identifying molecular signatures of environmental drivers of childhood overweight. Environ Int. 2025 Aug;202:109630. PMID: 40580709

Cell type-specific methylome-wide association studies of childhood ADHD symptoms

Meijer M, Klein M, Caramaschi D, Clark SL, Cosin-Tomas M, Koen N, Lu X, Mulder RH, Röder SW, Zhang Y, Zilich L, Bustamente M, Deuschle M, Felix JF, González JR, Gražulevičiene R, Streit F, Wright J, Carracedo A, Cecil CAM, Corpeleijn E, Hartman CA, Herberth G, Huels A, Relton C, Snieder H, Stein DJ, Sunyer J, Witt SH, Zar HJ, Zenclussen AC, Franke B, Copeland W, Aberg KA, van den Oord EJCG. Cell type-specific methylome-wide association studies of childhood ADHD symptoms. Eur Neuropsychopharmacol. 2025 Dec;101:7-17. PMID: 40321284

Early-life growth and emotional, behavior and cognitive outcomes in childhood and adolescence in the EU child cohort network: individual participant data meta-analysis of over 109,000 individuals

Gonçalves R, Blaauwendraad S, Avraam D, Beneíto A, Charles MA, Elhakeem A, Escribano J, Etienne L, García-Baquero Moneo G, Soares AG, de Groot J, Grote V, Gruszfeld D, Guerlich K, Guxens M, Heude B, Koletzko B, Lertxundi A, Lozano M, El Marroun H, McEachan R, Pinot de Moira A, Santorelli G, Strandberg-Larsen K, Tafflet M, Vainqueur C, Verduci E, Vrijheid M, Welten M, Wright J, Yang TC, Gaillard R, Jaddoe VWV. Early-life growth and emotional, behavior and cognitive outcomes in childhood and adolescence in the EU child cohort network: individual participant data meta-analysis of over 109,000 individuals. Lancet Reg Health Eur. 2025 Feb 26;52:101247. PMID: 40094119

Windows of susceptibility of prenatal and childhood exposure to air pollution and lung function at 6-8 years in the Spanish INMA (INfancia y Medio Ambiente) birth cohort

Domínguez A, Rivas I, Koch S, Binter AC, Iñiguez C, Estarlich M, Ferrero A, Lertxundi A, Zabaleta C, Nieuwenhuijsen M, Garcia-Aymerich J, Sunyer J, Vrijheid M, Guxens M, Casas M, Basagaña X. Windows of susceptibility of prenatal and childhood exposure to air pollution and lung function at 6-8 years in the Spanish INMA (INfancia y Medio Ambiente) birth cohort. Environ Res. 2025 Nov 15;285(Pt 4):122585. PMID: 40816673

Mapping of Determinants of Urinary Sex Steroid Metabolites During Late Pregnancy: Results from Two Spanish Cohorts

Laveriano-Santos EP, Renard-Dausset E, Bustamante M, Pelegri D, García-Ruiz Z, Ruiz-Rivera M, Cosin-Tomas M, Llurba-Olive E, Gomez-Roig MD, Haro N, Pozo ÓJ, Dadvand P, Vrijheid M, Maitre L. Mapping of Determinants of Urinary Sex Steroid Metabolites During Late Pregnancy: Results from Two Spanish Cohorts. Int J Mol Sci. 2025 Nov 29;26(23):11598. PMID: 41373750

Impact of pet ownership in early childhood at ages 1 and 4-5 years on mental health at ages 7-8: findings from the INMA project

González L, Guxens M, Sarzo B, Andiarena A, Santa-Marina L, Tardón A, Julvez J, Rodríguez-Dehli C, Rebagliato M, Estarlich M. Impact of pet ownership in early childhood at ages 1 and 4-5 years on mental health at ages 7-8: findings from the INMA project. World J Pediatr. 2025 Oct;21(10):1003-1016. PMID: 41045339

Investigating the relationship between neighbourhood characteristics, perceived social support and psychological wellbeing in Spanish adolescents

Piera Pi-Sunyer B, Bignardi G, García-Baquero G, Dadvand P, Vrijheid M, Guxens M, Esplugues A, Delgado-Saborit JM, Ibarluzea J, Blakemore SJ, Subiza-Pérez M. Investigating the relationship between neighbourhood characteristics, perceived social support and psychological wellbeing in Spanish adolescents. Sci Rep. 2025 Nov 6;15(1):38845. PMID: 41198832

Association between early-life exposure to mercury and cardiometabolic risk factors development in adolescence

Soler-Blasco R, Lozano M, Vallejo-Ortega J, Marina LS, Barroeta Z, Coscollá C, Iriarte G, Braeuer S, Ballester F, Llop S. Association between early-life exposure to mercury and cardiometabolic risk factors development in adolescence. Sci Total Environ. 2025 Dec 15;1008:180913. PMID: 41264948