Gipuzkoa

In May 2006 the INMA project was set up in Gipuzkoa with the aim of evaluating the role of the environmental pollutants present in the air, water and diet in the growth and development of the children. The incorporation of the women to the cohort was made coinciding with the first echography of pregnancy control. Biological samples were taken (blood, urine, hair, placenta, etc.) and a series of questionnaires were complimented (general, diet, labour, environmental, etc.) to evaluate the impact of the environmental pollutants present in the air and the water of consumption, as well as an estimation of the polluting agents contributed by the diet.

The mothers were recruited from population visiting at the Hospital of Zumarraga, which includes the municipalities of the Goierri and the Alto and Medio Urola. They were selected of this area because of the characteristics of the services of the hospital and primary attention centre, as well as by the environmental characteristics: hard presence of metallurgical industry, high density of traffic, low levels of products derived from the disinfection in the consumption water and a rich diet in fish, together with certain degree of hypothyroidism in the pregnant women.

Since then, the pursuit of 640 women has been made in first and the third trimester of pregnancy. At the moment the pursuit is being made of 623 children in aspects of growth and neurobehavioural development.

  • Funders of INMA-Gipuzkoa cohort:

This study was funded by grants from Instituto de Salud Carlos III (FIS-PI06/0867, FIS-PI09/00090, FIS-PI13/02187 and FIS-PI18/01142 incl. FEDER funds), CIBERESP, Department of Health of the Basque Government (2005111093, 2009111069, 2013111089 and 2015111065), and the Provincial Government of Gipuzkoa (DFG06/002, DFG08/001 and DFG15/221) and annual agreements with the municipalities of the study area (Zumarraga, Urretxu , Legazpi, Azkoitia y Azpeitia y Beasain).

  • Collaborating Entities:

Buscador

330 Results

Air pollution -
Reproductive health -


Ambient air pollution and low birthweight: a European cohort study (ESCAPE)

Pedersen M, Giorgis-Allemand L, Bernard C, Aguilera I, Andersen AM, Ballester F, Beelen RM, Chatzi L, Cirach M, Danileviciute A, Dedele A, Eijsden Mv, Estarlich M, Fernández-Somoano A, Fernández MF, Forastiere F, Gehring U, Grazuleviciene R, Gruzieva. Ambient air pollution and low birthweight: a European cohort study (ESCAPE). Lancet Respir Med. 2013 Nov;1(9):695-704. PMID: 24429273


Neurodevelopment -
Nutrition -


Iodine Supplementation During Pregnancy and Infant Neuropsychological Development. INMA Mother and Child Cohort Study

Rebagliato M, Murcia M, Alvarez-Pedrerol M, Espada M, Fernández-Somoano A, Lertxundi N, Navarrete-Muñoz EM, Forns J, Aranbarri A, Llop S, Julvez J, Tardón A, Ballester F. Iodine Supplementation During Pregnancy and Infant Neuropsychological Development: INMA Mother and Child Cohort Study. Am J Epidemiol. 2013 May 1;177(9):944-53.PMID: 23548753


Air pollution -
Respiratory health and atopy -


Prenatal exposure to cooking gas and respiratory health in infants is modified by tobacco smoke exposure and diet in the INMA birth cohort study

Esplugues A, Estarlich M, Sunyer J, Fuentes-Leonarte V, Basterrechea M, Vrijheid M, Riaño I, Santa-Marina L, Tardón A, Martinez D, Ballester F. Prenatal exposure to cooking gas and respiratory health in infants is modified by tobacco smoke exposure and diet in the INMA birth cohort study. Environ Health. 2013 Dec 1;12:100. PMID: 24289253


Intrauterine growth -
Tobacco -


Maternal smoking during pregnancy and fetal biometry: the INMA Mother and Child Cohort Study

Iñiguez C, Ballester F, Costa O, Murcia M, Souto A, Santa-Marina L, Aurrekoetxea JJ, Espada M, Vrijheid M, Alvarez-Avellón SM, Alvarez-Pedrerol M, Rebagliato M; INMA Study Investigators. Maternal smoking during pregnancy and fetal biometry: the INMA Mother and Child Cohort Study. Am J Epidemiol. 2013 Oct 1;178(7):1067-75. PMID: 24008909


Neurodevelopment -
Persistent organic compounds -


Prenatal and postnatal insecticide use and infant neuropsychological development in a multicenter birth cohort study

Llop S, Julvez J, Fernandez-Somoano A, Santa Marina L, Vizcaino E, Iñiguez C, Lertxundi N, Gascón M, Rebagliato M, Ballester F. Prenatal and postnatal insecticide use and infant neuropsychological development in a multicenter birth cohort study. Environ Int. 2013 Sep;59:175-82. PMID: 23831543


Respiratory health and atopy -
Water pollution -


Swimming pool attendance, respiratory symptoms and infections in the first year of life

Font-Ribera L, Villanueva CM, Ballester F, Santa Marina L, Tardón A, Espejo-Herrera N, Esplugues A, Rodríguez Dehli C, Basterrechea M, Sunyer J. Swimming pool attendance, respiratory symptoms and infections in the first year of life. Eur J Pediatr .2013 Jul;172(7):977-85. PMID: 23468123


Nutrition -
Respiratory health and atopy -


Mediterranean diet adherence during pregnancy and risk of wheeze and eczema in the first year of life: INMA (Spain) and RHEA (Greece) mother-child cohort studies

Chatzi L, Garcia R, Roumeliotaki T, Basterrechea M, Begiristain H, Iñiguez C, Vioque J, Kogevinas M, Sunyer J. Mediterranean diet adherence during pregnancy and risk of wheeze and eczema in the first year of life: INMA (Spain) and RHEA (Greece) mother-child cohort studies. Br J Nutr. 2013 Dec 14;110(11):2058-68. PMID: 23680284


Cleaning products -
Respiratory health and atopy -


The use of household cleaning products during pregnancy and lower respiratory tract infections and wheezing during early life

Casas L, Zock JP, Carsin AE, Fernandez-Somoano A, Esplugues A, Santa-Marina L, Tardón A, Ballester F, Basterrechea M, Sunyer J. The use of household cleaning products during pregnancy and lower respiratory tract infections and wheezing during early life. Int J Public Health. 2013 Oct;58(5):757-64. PMID: 23064260


Social inequalities -


Socio-Economic Inequalities in Health, Habits and Self-Care During Pregnancy in Spain

Larrañaga I, Santa-Marina L, Begiristain H, Machón M, Vrijheid M, Casas M, Tardón A, Fernández-Somoano A, Llop S, Rodriguez-Bernal CL, Fernandez MF. Socio-Economic Inequalities in Health, Habits and Self-Care During Pregnancy in Spain. Matern Child Health J. 2013 Sep;17(7):1315-24. PMID: 22983810


General about the Project -


Pregnancy and birth cohort resources in europe: a large opportunity for aetiological child health research

Larsen PS, Kamper-Jørgensen M, Adamson A, Barros H, Bonde JP, Brescianini S, Brophy S, Casas M, Devereux G, Eggesbø M, Fantini MP, Frey U, Gehring U, Grazuleviciene R, Henriksen TB, Hertz-Picciotto I, Heude B, Hryhorczuk DO, Inskip H, Jaddoe VW, Lawl. Pregnancy and birth cohort resources in europe: a large opportunity for aetiological child health research. Paediatr Perinat Epidemiol. 2013 Jul;27(4):393-414. PMID: 23772942


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