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REGISTRATION to the 18th INMA Scientific Conference

We announce the organization of the 18th INMA Scientific Conference 2023

  • Scientific Program: Link NEW!

These conference will follow the following format:

  • Plenary sessions and INMA results presentation: in person on February 7 and 8 in Parc de Recerca Biomedica de Barcelona – PRBB, Barcelona (it will be broadcast in Streaming)

Reserve these dates! We will wait for you!

  • REGISTRATION:
    Registration is mandatory
    since we need to have your data to send you the information so that you can attend, follow and connect by streaming to the different sessions.
    Send us an e-mail toinma@proyectoinma.org with this data (all fields are required!):

    • Subject for the e-mail: REGISTRATION INMA CONFERENCE 2023
    • Name:
    • Surname:
    • E-mail:
    • Relationship with the INMA Project:
      – Do you belong to any cohort of the INMA Project? to which?:
      – Do you collaborate with any cohort of the INMA Project? with which?:
      – Do you have an INMA External Collaboration proposal approved and under development?:
      – Are you external to the INMA Project?:
    • Your participation will be:
      – I will attend the sessions in person on February 7 in Barcelona: (Yes or No)
      – I will attend the sessions in person on February 8 in Barcelona: (Yes or No)
      – I will participate in the lunch (after closure) on February 8 in Barcelona: (Yes or No)
      – I will participate in the Social Activity on February 7: (Yes or No)
      – I will participate in the dinner on February 7 (no funded by the organization): (Yes or No)
      – I will follow the sessions on February 7 and 8 by Streaming: (Yes or No)

Registration will be open until January 10, 2023. EXTENSION: January 20, 2023

 

Collaborators:

                   


ANNOUNCEMENT of the 18th INMA Scientific Conference

We announce the organization of the 18th INMA Scientific Conference 2023

Days: 7 and 8 of February, 2023
Place: Barcelona

Reserve these dates! We will wait for you!

 

Collaborators:

                   

 


INMA: “Chronic stress in preadolescents: school context, bullying, and risk-taking behavior”

An INMA study investigated the influence of school environment and bullying on hair cortisol concentration. Hair cortisol concentration is a useful biomarker of long-term stress.

Although acute stress can be beneficial and adaptive, chronic stress is thought to be detrimental to several health outcomes, including the stress response. Bullying, defined as a type of aggressive behavior that occurs in the school environment, has been identified as one of the main stress sources among children and adolescents. The association between bullying and cortisol levels, a indicator of chronic stress, has been explored in some studies, and findings were inconsistent.

The main objective of the study was to determine whether bullying, along with other school-related factors (i.e., problems with peers, school environment, and academic performance) could predict chronic stress in preadolescents. Authors also considered whether risk-taking behaviors function and sex may modify this association.

At the 11-year-old visit, a total of 659 children from Gipuzkoa and Sabadell were included. Cortisol concentrations were measured in hair strands of 3cm, to reflect the chronic stress of the past 3 months. Bullying experience in the past 2 months were estimated using the validated Olweus Bully Victim Questionnaire. Other environmental and behavioral variables, including school environment, problems with peers, risky decision making and academic achievement, were recorded using questionnaires at the 11-year-old visit.

The results suggest that being involved as a bully or a victim was related to higher cortisol levels and, higher cortisol concentration was associated with more risk-taking behavior. This is the first study showing the association of different roles that children may take in bullying with cortisol concentration. Authors say that the study “allows to gain a deeper understanding of the relationship between school stressors and neurophysiological function”. Besides, they plead for programs of prevention and intervention that “could modify individual physiological responses to stress and reduce the effects of stress on the health”.

Reference: Babarro I, Ibarluzea J, Theodorsson E, Fano E, Lebeña A, Guxens M, Sunyer J, Andiarena A. Hair cortisol as a biomarker of chronic stress in preadolescents: influence of school context and bullying. Child Neuropsychol. 2022 Aug 28:1-18. doi: 10.1080/09297049.2022.2115991. Epub ahead of print. PMID: 36036166.

Link to the scientific article: https://www.tandfonline.com/doi/full/10.1080/09297049.2022.2115991


Identification of autosomal cis expression quantitative trait methylation (cis eQTMs) in children’s blood

Ruiz-Arenas C, Hernandez-Ferrer C, Vives-Usano M, Marí S, Quintela I, Mason D, Cadiou S, Casas M, Andrusaityte S, Gutzkow KB, Vafeiadi M, Wright J, Lepeule J, Grazuleviciene R, Chatzi L, Carracedo Á, Estivill X, Marti E, Escaramís G, Vrijheid M, González JR, Bustamante M. Identification of autosomal cis expression quantitative trait methylation (cis eQTMs) in children’s blood. Elife. 2022 Mar 18;11:e65310. PMID: 35302492


Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation

Solomon O, Huen K, Yousefi P, Küpers LK, González JR, Suderman M, Reese SE, Page CM, Gruzieva O, Rzehak P, Gao L, Bakulski KM, Novoloaca A, Allard C, Pappa I, Llambrich M, Vives M, Jima DD, Kvist T, Baccarelli A, White C, Rezwan FI, Sharp GC, Tindula G, Bergström A, Grote V, Dou JF, Isaevska E, Magnus MC, Corpeleijn E, Perron P, Jaddoe VWV, Nohr EA, Maitre L, Foraster M, Hoyo C, Håberg SE, Lahti J, DeMeo DL, Zhang H, Karmaus W, Kull I, Koletzko B, Feinberg JI, Gagliardi L, Bouchard L, Ramlau-Hansen CH, Tiemeier H, Santorelli G, Maguire RL, Czamara D, Litonjua AA, Langhendries JP, Plusquin M, Lepeule J, Binder EB, Verduci E, Dwyer T, Carracedo Á, Ferre N, Eskenazi B, Kogevinas M, Nawrot TS, Munthe-Kaas MC, Herceg Z, Relton C, Melén E, Gruszfeld D, Breton C, Fallin MD, Ghantous A, Nystad W, Heude B, Snieder H, Hivert MF, Felix JF, Sørensen TIA, Bustamante M, Murphy SK, Raikkönen K, Oken E, Holloway JW, Arshad SH, London SJ, Holland N. Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation. Mutat Res Rev Mutat Res. 2022 Jan-Jun;789:108415. PMID: 35690418


Environmental and dietary determinants of metal exposure in four-year-old children from a cohort located in an industrial area (Asturias, Northern Spain)

Junqué E, Tardón A, Fernandez-Somoano A, Grimalt JO. Environmental and dietary determinants of metal exposure in four-year-old children from a cohort located in an industrial area (Asturias, Northern Spain). Environ Res. 2022 Jul 15:113862. doi: 10.1016/j.envres.2022.113862. Epub ahead of print. PMID: 35850295


Serum concentrations of persistent organic pollutants mixture during pregnancy and anogenital distance in 8-year-old children from the INMA-Asturias cohort

García-Villarino M, Signes-Pastor AJ, Riaño-Galán I, Rodríguez-Dehli AC, Vizcaíno E, Grimalt JO, Fernández-Somoano A, Tardón A. Serum concentrations of persistent organic pollutants mixture during pregnancy and anogenital distance in 8-year-old children from the INMA-Asturias cohort. Environ Res. 2022 Jun 9;213:113607. doi: 10.1016/j.envres.2022.113607. Epub ahead of print. PMID: 35690090


Do prepubertal hormones, 2D:4D index and psychosocial context jointly explain 11-year-old preadolescents’ involvement in bullying?

Babarro I, Andiarena A, Fano E, García-Baquero G, Lebeña A, Arranz-Freijo EB, Ibarluzea J. Do prepubertal hormones, 2D:4D index and psychosocial context jointly explain 11-year-old preadolescents’ involvement in bullying? Biol Psychol. 2022 Jul;172:108379. PMID: 35690279


Pre and postnatal exposure to mercury and sexual development in 9-year-old children in Spain: The role of brain-derived neurotrophic factor

Sarzo B, Ballester F, Soler-Blasco R, Lopez-Espinosa MJ, Lozano M, Iriarte G, Beneito A, Riutort-Mayol G, Murcia M, Llop S. Pre and postnatal exposure to mercury and sexual development in 9-year-old children in Spain: The role of brain-derived neurotrophic factor. Environ Res. 2022 Jun 10;213:113620. doi: 10.1016/j.envres.2022.113620. Epub ahead of print. PMID: 35697081


Genome-wide Association Meta-analysis of Childhood and Adolescent Internalizing Symptoms

Jami ES, Hammerschlag AR, Ip HF, Allegrini AG, Benyamin B, Border R, Diemer EW, Jiang C, Karhunen V, Lu Y, Lu Q, Mallard TT, Mishra PP, Nolte IM, Palviainen T, Peterson RE, Sallis HM, Shabalin AA, Tate AE, Thiering E, Vilor-Tejedor N, Wang C, Zhou A, Adkins DE, Alemany S, Ask H, Chen Q, Corley RP, Ehli EA, Evans LM, Havdahl A, Hagenbeek FA, Hakulinen C, Henders AK, Hottenga JJ, Korhonen T, Mamun A, Marrington S, Neumann A, Rimfeld K, Rivadeneira F, Silberg JL, van Beijsterveldt CE, Vuoksimaa E, Whipp AM, Tong X, Andreassen OA, Boomsma DI, Brown SA, Burt SA, Copeland W, Dick DM, Harden KP, Harris KM, Hartman CA, Heinrich J, Hewitt JK, Hopfer C, Hypponen E, Jarvelin MR, Kaprio J, Keltikangas-Järvinen L, Klump KL, Krauter K, Kuja-Halkola R, Larsson H, Lehtimäki T, Lichtenstein P, Lundström S, Maes HH, Magnus P, Munafò MR, Najman JM, Njølstad PR, Oldehinkel AJ, Pennell CE, Plomin R, Reichborn-Kjennerud T, Reynolds C, Rose RJ, Smolen A, Snieder H, Stallings M, Standl M, Sunyer J, Tiemeier H, Wadsworth SJ, Wall TL, Whitehouse AJO, Williams GM, Ystrøm E, Nivard MG, Bartels M, Middeldorp CM. Genome-wide Association Meta-analysis of Childhood and Adolescent Internalizing Symptoms. J Am Acad Child Adolesc Psychiatry. 2022 Jul;61(7):934-945. PMID: 35378236


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