Results
Worldwide trends in diabetes prevalence and treatment from 1990 to 2022: a pooled analysis of 1108 population-representative studies with 141 million participants
NCD Risk Factor Collaboration (NCD-RisC). Worldwide trends in diabetes prevalence and treatment from 1990 to 2022: a pooled analysis of 1108 population-representative studies with 141 million participants. Lancet. 2024 Nov 23;404(10467):2077-2093. PMID: 39549716
Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults
NCD Risk Factor Collaboration (NCD-RisC). Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults. Lancet. 2024 Mar 16;403(10431):1027-1050. PMID: 38432237
Early childcare arrangements and children’s internalizing and externalizing symptoms: an individual participant data meta-analysis of six prospective birth cohorts in Europe
Barry KM, Avraam D, Cadman T, Elhakeem A, El Marroun H, Jansen PW, Nybo-Andersen AM, Strandberg-Larsen K, Safont LG, Soler-Blasco R, Barreto-Zarza F, Julvez J, Vrijheid M, Heude B, Charles MA, Gomajee AR, Melchior M. Early childcare arrangements and children’s internalizing and externalizing symptoms: an individual participant data meta-analysis of six prospective birth cohorts in Europe. Lancet Reg Health Eur. 2024 Aug 21;45:101036. PMID: 39262448
Socioeconomic position during pregnancy and pre-school exposome in children from eight European birth cohort studies
Pizzi C, Moirano G, Moccia C, Maule M, D’Errico A, Vrijheid M, Cadman TJ, Fossati S, Nieuwenhuijsen M, Beneito A, Calas L, Duijts L, Elhakeem A, Harris JR, Heude B, Jaddoe V, Lawlor DA, Lioret S, McEachan RR, Nader JL, Pedersen M, Pinot de Moira A, Strandberg-Larsen K, Subiza-Pérez M, Vafeiadi M, Welten M, Wright J, Yang TC, Richiardi L. Socioeconomic position during pregnancy and pre-school exposome in children from eight European birth cohort studies. Soc Sci Med. 2024 Oct;359:117275. PMID: 39236481
Urban environment exposures, energy balance-related behaviors and their combination in preschoolers from three European countries
Descarpentrie A, Dargent-Molina P, Arregi A, Carrasco P, Estarlich M, Guxens M, McEachan R, Nieuwenhuijsen M, Subiza-Pérez M, Wright J, Charles MA, Heude B, Vrijheid M, Lioret S. Urban environment exposures, energy balance-related behaviors and their combination in preschoolers from three European countries. Environ Int. 2024 Aug;190:108880. PMID: 39024825
The association of Helicobacter pylori with adverse pregnancy outcomes in three European birth cohorts
Galan R, Pembrey L, Bustamante M, Aguilar R, Mason D, Vidal M, Bañuls M, Roumeliotaki T, Delgado-Saborit JM, Marin N, Vrijheid M, Bempi V, Moncunill G, Dobaño C, Kogevinas M, Karachaliou M. The association of Helicobacter pylori with adverse pregnancy outcomes in three European birth cohorts. BMC Pregnancy Childbirth. 2024 Nov 12;24(1):745. PMID: 39533217
Early life exposure to mercury and relationships with telomere length and mitochondrial DNA content in European children
Lozano M, McEachan RRC, Wright J, Yang TC, Dow C, Kadawathagedara M, Lepeule J, Bustamante M, Maitre L, Vrijheid M, Brantsæter AL, Meltzer HM, Bempi V, Roumeliotaki T, Thomsen C, Nawrot T, Broberg K, Llop S. Early life exposure to mercury and relationships with telomere length and mitochondrial DNA content in European children. Sci Total Environ. 2024 Jul 1;932:173014. PMID: 38729362.
Green space exposure and blood DNA methylation at birth and in childhood – A multi-cohort study
Aguilar-Lacasaña S, Fontes Marques I, de Castro M, Dadvand P, Escribà X, Fossati S, González JR, Nieuwenhuijsen M, Alfano R, Annesi-Maesano I, Brescianini S, Burrows K, Calas L, Elhakeem A, Heude B, Hough A, Isaevska E, W V Jaddoe V, Lawlor DA, Monaghan G, Nawrot T, Plusquin M, Richiardi L, Watmuff A, Yang TC, Vrijheid M, F Felix J, Bustamante M. Green space exposure and blood DNA methylation at birth and in childhood – A multi-cohort study. Environ Int. 2024 Jun;188:108684. PMID: 38776651.
Integrating Multi-Omics with environmental data for precision health: A novel analytic framework and case study on prenatal mercury induced childhood fatty liver disease
Goodrich JA, Wang H, Jia Q, Stratakis N, Zhao Y, Maitre L, Bustamante M, Vafeiadi M, Aung M, Andrušaitytė S, Basagana X, Farzan SF, Heude B, Keun H, McConnell R, Yang TC, Siskos AP, Urquiza J, Valvi D, Varo N, Småstuen Haug L, Oftedal BM, Gražulevičienė R, Philippat C, Wright J, Vrijheid M, Chatzi L, Conti DV. Integrating Multi-Omics with environmental data for precision health: A novel analytic framework and case study on prenatal mercury induced childhood fatty liver disease. Environ Int. 2024 Aug;190:108930. PMID: 39128376
Cesarean delivery and blood DNA methylation at birth and childhood: Meta-analysis in the Pregnancy and Childhood Epigenetics Consortium
Wang S, Casey E, Sordillo J, Aguilar-Lacasaña S, Morales Berstein F, Biedrzycki RJ, Brescianini S, Chen S, Hough A, Isaevska E, Kim WJ, Lecorguillé M, Li SS, Page CM, Park J, Röder S, Salontaji K, Santorelli G, Sun Y, Won S, Zillich E, Zillich L, Annesi-Maesano I, Arshad SH, Bustamante M, Cecil CAM, Elliott HR, Ewart S, Felix JF, Gagliardi L, Håberg SE, Herberth G, Heude B, Holloway JW, Huels A, Karmaus W, Koppelman GH, London SJ, Mumford SL, Nisticò L, Popovic M, Rusconi F, Schisterman EF, Stein DJ, Send T, Tiemeier H, Vonk JM, Vrijheid M, Wiemels JL, Witt SH, Wright J, Yeung EH, Zar HJ, Zenclussen AC, Zhang H, Chavarro JE, Hivert MF. Cesarean delivery and blood DNA methylation at birth and childhood: Meta-analysis in the Pregnancy and Childhood Epigenetics Consortium. Sci Adv. 2024 Nov 29;10(48):eadr2084. PMID: 39602535
Machine learning-based health environmental-clinical risk scores in European children
Guimbaud JB, Siskos AP, Sakhi AK, Heude B, Sabidó E, Borràs E, Keun H, Wright J, Julvez J, Urquiza J, Gützkow KB, Chatzi L, Casas M, Bustamante M, Nieuwenhuijsen M, Vrijheid M, López-Vicente M, de Castro Pascual M, Stratakis N, Robinson O, Grazuleviciene R, Slama R, Alemany S, Basagaña X, Plantevit M, Cazabet R, Maitre L. Machine learning-based health environmental-clinical risk scores in European children. Commun Med (Lond). 2024 May 23;4(1):98. PMID: 38783062
Association of Gestational Free and Total Triiodothyronine With Gestational Hypertension, Preeclampsia, Preterm Birth, and Birth Weight: An Individual Participant Data Meta-analysis
Derakhshan A, Männistö T, Chen L, Osinga JAJ, Ashoor G, Lu X, Bliddal S, Tao FB, Brown SJ, Vaidya B, Hattersley AT, Itoh S, Popova PV, Aminorroaya A, Kishi R, Kianpour M, Vasukova EA, López-Bermejo A, Oken E, Chatzi L, Vafeiadi M, Bramer WM, Bassols J, Lertxundi A, Fernández-Somoano A, Carrasco P, Auvinen J, Huang K, Feldt-Rasmussen U, Grineva EN, Alexander EK, Pearce EN, Chaker L, Walsh JP, Peeters RP, Guxens M, Suvanto E, Nicolaides KH, Korevaar TIM. Association of Gestational Free and Total Triiodothyronine With Gestational Hypertension, Preeclampsia, Preterm Birth, and Birth Weight: An Individual Participant Data Meta-analysis. J Clin Endocrinol Metab. 2024 Feb 20;109(3):e1290-e1298. PMID: 37878891
Hair cortisol determinants in 11-year-old children: Environmental, social and individual factors
Arregi A, Vegas O, Lertxundi A, García-Baquero G, Ibarluzea J, Andiarena A, Babarro I, Subiza-Pérez M, Lertxundi N. Hair cortisol determinants in 11-year-old children: Environmental, social and individual factors. Horm Behav. 2024 Aug;164:105575. PMID: 38851169
Brain-derived neurotrophic factor (BDNF): an effect biomarker of neurodevelopment in human biomonitoring programs
Rodríguez-Carrillo A, Verheyen VJ, Van Nuijs ALN, Fernández MF, Remy S. Brain-derived neurotrophic factor (BDNF): an effect biomarker of neurodevelopment in human biomonitoring programs. Front Toxicol. 2024 Jan 10;5:1319788. PMID: 38268968
Pro-vegetarian dietary patterns and essential and heavy metal exposure in children of 4-5-years from the INfancia y medio Ambiente cohort (INMA)
Oncina-Cánovas A, Vioque J, Riutort-Mayol G, Soler-Blasco R, Irizar A, Barroeta Z, Fernández-Somoano A, Tardón A, Vrijheid M, Guxens M, Carey M, Meharg C, Ralphs K, McCreanor C, Meharg A, Signes-Pastor AJ. Pro-vegetarian dietary patterns and essential and heavy metal exposure in children of 4-5-years from the INfancia y medio Ambiente cohort (INMA). Int J Hyg Environ Health. 2024 Apr;257:114344. PMID: 38430670
Risk Factors for Thyroid Dysfunction in Pregnancy: An Individual Participant Data Meta-Analysis
Osinga JAJ, Liu Y, Männistö T, Vafeiadi M, Tao FB, Vaidya B, Vrijkotte TGM, Mosso L, Bassols J, López-Bermejo A, Boucai L, Aminorroaya A, Feldt-Rasmussen U, Hisada A, Yoshinaga J, Broeren MAC, Itoh S, Kishi R, Ashoor G, Chen L, Veltri F, Lu X, Taylor PN, Brown SJ, Chatzi L, Popova PV, Grineva EN, Ghafoor F, Pirzada A, Kianpour M, Oken E, Suvanto E, Hattersley A, Rebagliato M, Riaño-Galán I, Irizar A, Vrijheid M, Delgado-Saborit JM, Fernández-Somoano A, Santa-Marina L, Boelaert K, Brenta G, Dhillon-Smith R, Dosiou C, Eaton JL, Guan H, Lee SY, Maraka S, Morris-Wiseman LF, Nguyen CT, Shan Z, Guxens M, Pop VJM, Walsh JP, Nicolaides KH, D’Alton ME, Visser WE, Carty DM, Delles C, Nelson SM, Alexander EK, Chaker L, Palomaki GE, Peeters RP, Bliddal S, Huang K, Poppe KG, Pearce EN, Derakhshan A, Korevaar TIM. Risk Factors for Thyroid Dysfunction in Pregnancy: An Individual Participant Data Meta-Analysis. Thyroid. 2024 May;34(5):646-658. PMID: 38546971
Nitrogen dioxide exposure, attentional function, and working memory in children from 4 to 8 years: Periods of susceptibility from pregnancy to childhood
Crooijmans KLHA, Iñiguez C, Withworth KW, Estarlich M, Lertxundi A, Fernández-Somoano A, Tardón A, Ibarluzea J, Sunyer J, Guxens M, Binter AC. Nitrogen dioxide exposure, attentional function, and working memory in children from 4 to 8 years: Periods of susceptibility from pregnancy to childhood. Environ Int. 2024 Apr;186:108604. PMID: 38564945
Evaluating the association between placenta DNA methylation and cognitive functions in the offspring
Diez-Ahijado L, Cilleros-Portet A, Fernández-Jimenez N, Fernández MF, Guxens M, Julvez J, Llop S, Lopez-Espinosa MJ, Subiza-Pérez M, Lozano M, Ibarluzea J, Sunyer J, Bustamante M, Cosin-Tomas M. Evaluating the association between placenta DNA methylation and cognitive functions in the offspring. Transl Psychiatry. 2024 Sep 20;14(1):383. PMID: 39304652
Maternal age is related to offspring DNA methylation: A meta-analysis of results from the PACE consortium
Yeung E, Biedrzycki RJ, Gómez Herrera LC, Issarapu P, Dou J, Marques IF, Mansuri SR, Page CM, Harbs J, Khodasevich D, Poisel E, Niu Z, Allard C, Casey E, Berstein FM, Mancano G, Elliott HR, Richmond R, He Y, Ronkainen J, Sebert S, Bell EM, Sharp G, Mumford SL, Schisterman EF, Chandak GR, Fall CHD, Sahariah SA, Silver MJ, Prentice AM, Bouchard L, Domellof M, West C, Holland N, Cardenas A, Eskenazi B, Zillich L, Witt SH, Send T, Breton C, Bakulski KM, Fallin MD, Schmidt RJ, Stein DJ, Zar HJ, Jaddoe VWV, Wright J, Grazuleviciene R, Gutzkow KB, Sunyer J, Huels A, Vrijheid M, Harlid S, London S, Hivert MF, Felix J, Bustamante M, Guan W. Maternal age is related to offspring DNA methylation: A meta-analysis of results from the PACE consortium. Aging Cell. 2024 Aug;23(8):e14194. PMID: 38808605
Potentially causal associations between placental DNA methylation and schizophrenia and other neuropsychiatric disorders
Cilleros-Portet A, Lesseur C, Marí S, Cosin-Tomas M, Lozano M, Irizar A, Burt A, García-Santisteban I, Garrido-Martín D, Escaramís G, Hernangomez-Laderas A, Soler-Blasco R, Breeze CE, Gonzalez-Garcia BP, Santa-Marina L, Chen J, Llop S, Fernández MF, Vrijheid M, Ibarluzea J, Guxens M, Marsit C, Bustamante M, Bilbao JR, Fernandez-Jimenez N. Potentially causal associations between placental DNA methylation and schizophrenia and other neuropsychiatric disorders. Nat Commun. 2025 Mar 14;16(1):2431. PMID: 40087310
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