Results
Outdoor air pollution, road traffic noise, and allostatic load in children aged 6-11 years: evidence from six European cohorts
Mou Y, Kusters MSW, Robinson O, Maitre L, McEachan RRC, Yuan WL, Hjertager Krog N, Andrušaitytė S, Bustamante M, de Castro Pascual M, Dedele A, Wright J, Grazuleviciene R, Aasvang GM, Lepeule J, Nieuwenhuijsen M, Tiemeier H, Vrijheid M, Thomson EM, Guxens M. Outdoor air pollution, road traffic noise, and allostatic load in children aged 6-11 years: evidence from six European cohorts. Eur J Epidemiol. 2025 May;40(5):537-548. PMID: 40366609
Epistasis of ERAP1 With 4 Major Histocompatibility Complex Class I Alleles in Frontal Fibrosing Alopecia: A Genome-Wide Association Study Meta-Analysis
Rayinda T, Dand N, McSweeney SM, Christou E, Ung CY, Stefanato CM, Fenton DA, Harries M, Palamaras I, Tidman A, Holmes S, Koutalopoulou A, Ardern-Jones M, Kaur M, Papanikou S, Chasapi V, Vañó-Galvan S, Saceda-Corralo D, Melián-Olivera A, Azcarraga-Llobet C, Lobato-Berezo A, Bustamante M, Sunyer J, Starace MVR, Piraccini BM, Wiss IP, Senna MM, Singh R, Hillmann K, Kanti-Schmidt V, Blume-Peytavi U, McGrath JA, Simpson MA, Tziotzios C. Epistasis of ERAP1 With 4 Major Histocompatibility Complex Class I Alleles in Frontal Fibrosing Alopecia: A Genome-Wide Association Study Meta-Analysis. JAMA Dermatol. 2025 Mar 1;161(3):310-314. PMID: 39937552
Genetic characterization of preschool wheeze phenotypes
Fischer-Rasmussen K, Granell R, Eliasen AU, Kreiner E, Pedersen CT, Luo Y, Chawes B, Stokholm J, Malby Schoos AM, Kumar A, Nybo Andersen AM, Feenstra B, Geller F, Siroux V, Demenais F, Bouzigon E, Jaddoe V, van der Valk RJP, Duijts L, Sunyer J, Guxens M, Marinelli M, Bustamante M, Heinrich J, Standl M, Curtin J, Simpson A, Murray C, Jacobsson B, Myhre R, Pennell CE, Daley D, Ober C, Gern JE, Jackson D, Boomsma DI, Hottenga JJ, Abdellaoui A, Holloway JW, Collins S, Turner S, Arshad SH, Ullah A, Melén E, Henderson J, Bisgaard H, Pedersen AG, Custovic A, Vonk JM, Koppelman GH, Kabesch M, Bønnelykke K; Multidisciplinary Study to Identify the Genetic and Environmental Causes of Asthma in the European Community (GABRIEL) consortium; EArly Genetics and Lifecourse Epidemiology (EAGLE) consortium. Genetic characterization of preschool wheeze phenotypes. J Allergy Clin Immunol. 2025 Dec;156(6):1537-1546. PMID: 40769318
Understanding Social Inequalities in Childhood Asthma: Quantifying the Mediating Role of Modifiable Early-Life Risk Factors in Seven European Birth Cohorts
Pinot de Moira A, Aurup AV, Avraam D, Zugna D, Jensen AKG, Welten M, Cadman T, de Lauzon-Guillain B, Duijts L, Elhakeem A, Esplugues A, Garcia-Aymerich J, García-Baquero G, González Safont L, Harris JR, Iñiguez C, Jaddoe VWV, McEachan RRC, Nader JLT, Santa Marina L, Swertz MA, Tafflet M, Vrijheid M, Wright J, Yang TC, Taylor-Robinson D, Richiardi L, Nybo Andersen AM. Understanding Social Inequalities in Childhood Asthma: Quantifying the Mediating Role of Modifiable Early-Life Risk Factors in Seven European Birth Cohorts. J Allergy Clin Immunol Pract. 2025 Jun;13(6):1385-1396. PMID: 40314625
Association of environmental noise exposure with cortisol levels in children from eight European birth cohorts
Arregi A, Robinson O, Aasvang GM, Andrusaityte S, Dedele A, Evandt J, Garcia-Baquero G, Krog NH, Guxens M, Jaddoe VWV, Karachaliou M, Lertxundi A, Margetaki K, McEachan R, Nieuwenhuijsen M, Philippat C, Pozo OJ, Slama R, Subiza-Pérez M, van Rossum EFC, Vrijheid M, Wright J, Yang TC, Vegas O, Lertxundi N. Association of environmental noise exposure with cortisol levels in children from eight European birth cohorts. Environ Res. 2025 Jul 15;277:121541. PMID: 40203977
Particulate matter exposure during pregnancy and birth outcomes: exposure windows of susceptibility and socioeconomic inequalities
Guxens M, Botella N, Stafoggia M, Canto M, Petricola S, Valentín A, Lertxundi A, Fernández-Somoano A, Freire C, García-Altés A, Diez E, Marí-Dell’Olmo M, Iñiguez C, López MJ, Ramis R, Binter AC. Particulate matter exposure during pregnancy and birth outcomes: exposure windows of susceptibility and socioeconomic inequalities. Eur J Epidemiol. 2025 Sep;40(9):1105-1121. PMID: 40705228
Meet-in-the-middle meets multi-omics identifying molecular signatures of environmental drivers of childhood overweight
Wang C, Reimann B, Nawrot TS, Martens DS, Wright J, McEachan R, Lepeule J, Yuan W, Chatzi L, Vafeiadi M, Grazuleviciene R, Andrusaityte S, Robinson O, Sunyer J, Keun H, Lau CE, Siskos AP, Coen M, Borràs E, Sabidó E, González JR, Vives-Usano M, Estivill X, Carracedo A, Ruiz-Arenas C, Quintela I, Casas M, Nieuwenhuijsen M, Tamayo I, Gutzkow KB, Thomsen C, Sakhi AK, Bustamante M, Maitre L, Vrijheid M, Plusquin M, Alfano R. Meet-in-the-middle meets multi-omics identifying molecular signatures of environmental drivers of childhood overweight. Environ Int. 2025 Aug;202:109630. PMID: 40580709
Cell type-specific methylome-wide association studies of childhood ADHD symptoms
Meijer M, Klein M, Caramaschi D, Clark SL, Cosin-Tomas M, Koen N, Lu X, Mulder RH, Röder SW, Zhang Y, Zilich L, Bustamente M, Deuschle M, Felix JF, González JR, Gražulevičiene R, Streit F, Wright J, Carracedo A, Cecil CAM, Corpeleijn E, Hartman CA, Herberth G, Huels A, Relton C, Snieder H, Stein DJ, Sunyer J, Witt SH, Zar HJ, Zenclussen AC, Franke B, Copeland W, Aberg KA, van den Oord EJCG. Cell type-specific methylome-wide association studies of childhood ADHD symptoms. Eur Neuropsychopharmacol. 2025 Dec;101:7-17. PMID: 40321284
Early-life growth and emotional, behavior and cognitive outcomes in childhood and adolescence in the EU child cohort network: individual participant data meta-analysis of over 109,000 individuals
Gonçalves R, Blaauwendraad S, Avraam D, Beneíto A, Charles MA, Elhakeem A, Escribano J, Etienne L, García-Baquero Moneo G, Soares AG, de Groot J, Grote V, Gruszfeld D, Guerlich K, Guxens M, Heude B, Koletzko B, Lertxundi A, Lozano M, El Marroun H, McEachan R, Pinot de Moira A, Santorelli G, Strandberg-Larsen K, Tafflet M, Vainqueur C, Verduci E, Vrijheid M, Welten M, Wright J, Yang TC, Gaillard R, Jaddoe VWV. Early-life growth and emotional, behavior and cognitive outcomes in childhood and adolescence in the EU child cohort network: individual participant data meta-analysis of over 109,000 individuals. Lancet Reg Health Eur. 2025 Feb 26;52:101247. PMID: 40094119
Windows of susceptibility of prenatal and childhood exposure to air pollution and lung function at 6-8 years in the Spanish INMA (INfancia y Medio Ambiente) birth cohort
Domínguez A, Rivas I, Koch S, Binter AC, Iñiguez C, Estarlich M, Ferrero A, Lertxundi A, Zabaleta C, Nieuwenhuijsen M, Garcia-Aymerich J, Sunyer J, Vrijheid M, Guxens M, Casas M, Basagaña X. Windows of susceptibility of prenatal and childhood exposure to air pollution and lung function at 6-8 years in the Spanish INMA (INfancia y Medio Ambiente) birth cohort. Environ Res. 2025 Nov 15;285(Pt 4):122585. PMID: 40816673
Mapping of Determinants of Urinary Sex Steroid Metabolites During Late Pregnancy: Results from Two Spanish Cohorts
Laveriano-Santos EP, Renard-Dausset E, Bustamante M, Pelegri D, García-Ruiz Z, Ruiz-Rivera M, Cosin-Tomas M, Llurba-Olive E, Gomez-Roig MD, Haro N, Pozo ÓJ, Dadvand P, Vrijheid M, Maitre L. Mapping of Determinants of Urinary Sex Steroid Metabolites During Late Pregnancy: Results from Two Spanish Cohorts. Int J Mol Sci. 2025 Nov 29;26(23):11598. PMID: 41373750
Impact of pet ownership in early childhood at ages 1 and 4-5 years on mental health at ages 7-8: findings from the INMA project
González L, Guxens M, Sarzo B, Andiarena A, Santa-Marina L, Tardón A, Julvez J, Rodríguez-Dehli C, Rebagliato M, Estarlich M. Impact of pet ownership in early childhood at ages 1 and 4-5 years on mental health at ages 7-8: findings from the INMA project. World J Pediatr. 2025 Oct;21(10):1003-1016. PMID: 41045339
Investigating the relationship between neighbourhood characteristics, perceived social support and psychological wellbeing in Spanish adolescents
Piera Pi-Sunyer B, Bignardi G, García-Baquero G, Dadvand P, Vrijheid M, Guxens M, Esplugues A, Delgado-Saborit JM, Ibarluzea J, Blakemore SJ, Subiza-Pérez M. Investigating the relationship between neighbourhood characteristics, perceived social support and psychological wellbeing in Spanish adolescents. Sci Rep. 2025 Nov 6;15(1):38845. PMID: 41198832
Association between early-life exposure to mercury and cardiometabolic risk factors development in adolescence
Soler-Blasco R, Lozano M, Vallejo-Ortega J, Marina LS, Barroeta Z, Coscollá C, Iriarte G, Braeuer S, Ballester F, Llop S. Association between early-life exposure to mercury and cardiometabolic risk factors development in adolescence. Sci Total Environ. 2025 Dec 15;1008:180913. PMID: 41264948
Assessing metal mixture effects on neuropsychological development: A trade-off between complexity and interpretability
Diaz-Coto S, Notario-Barandiaran L, Martinez-Camblor P, Lozano M, Llop S, Tardón A, Rodríguez-Dehli C, Irizar A, Lertxundi N, Guxens M, Julvez J, Signes-Pastor AJ. Assessing metal mixture effects on neuropsychological development: A trade-off between complexity and interpretability. Int J Hyg Environ Health. 2026 Jan;271:114697. PMID: 41124768.
Exposure to high temperature and sleep in preadolescents from two European birth cohorts
Essers E, Granés L, Botella N, Petricola S, González-Safont L, Arregi A, Vegas O, Vrijheid M, Iñiguez C, El Marroun H, Tiemeier H, Guxens M. Exposure to high temperature and sleep in preadolescents from two European birth cohorts. Environ Int. 2025 Jun;200:109543. PMID: 40424701
Mixtures of chemicals in pregnancy and their effects on cognitive and fine motor abilities in childhood
Brennan Kearns P, González L, Soler-Blasco R, Andiarena A, Santa-Marina L, Casas M, Burgaleta M, Vrijheid M, Guxens M. Mixtures of chemicals in pregnancy and their effects on cognitive and fine motor abilities in childhood. Environ Res. 2025 Nov 15;285(Pt 2):122380. PMID: 40692023
Seroepidemiology of maternal and childhood pathogen exposure in three European mother-child cohorts
Karachaliou M, Vidal M, Pembrey L, Bustamante M, Espinosa A, Mason D, Bañuls M, Casabonne D, Roumeliotaki T, Bempi V, Marin N, Delgado-Saborit JM, Loreto SMR, Ibarluzea J, Vrijheid M, Aguilar R, Dobaño C, Kogevinas M. Seroepidemiology of maternal and childhood pathogen exposure in three European mother-child cohorts. Int J Infect Dis. 2025 Oct;159:107994. PMID: 40701399
Maternal nut and fish consumption during pregnancy and child risky decision-making at 11 years old
Rivera MR, Pinar-Martí A, Babarro I, Ibarluzea J, Vioque J, Llop S, Fernández-Somoano A, Tardón A, Pascual-Rubio V, Fabregat-Sanjuan A, Fernández-Barrés S, Romaguera D, Guxens M, Julvez J. Maternal nut and fish consumption during pregnancy and child risky decision-making at 11 years old. Eur Child Adolesc Psychiatry. 2025 Nov;34(11):3643-3654. PMID: 40493090. Comment: Eur Child Adolesc Psychiatry. 2026 Jan;35(1):295-296. PMID: 40928651. Response: Eur Child Adolesc Psychiatry. 2026 Jan;35(1):301-302. PMID: 41042371
Telomere Length and Emotional and Behavioral Problems in Children from the Prospective Birth Cohort INfancia y Medio Ambiente (INMA) Study
Campos-Sánchez I, Navarrete-Muñoz EM, Barber-Valles JX, Martens DS, Riaño-Galán I, Irizar A, Llop S, Guxens M, Rodríguez-Dehli C, Babarro I, Lozano M, Vrijheid M, Nawrot T, Valera-Gran D. Telomere Length and Emotional and Behavioral Problems in Children from the Prospective Birth Cohort INfancia y Medio Ambiente (INMA) Study. Children (Basel). 2025 Jul 2;12(7):875. PMID: 40723068
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