Valencia

In October 2003 the pilot study for the creation of the INMA cohort in Valencia was carried out. In February 2004 started the recruitment of the cohort that went on until June 2005. 855 women that belonged to the departments of health 6 (34 municipalities) and 7 (two quarters of Valencia) were recruited. They were selected by consecutive sampling of among all those of the area of study that went to the population sieving of the syndrome of Down that is carried out among the 10-13 weeks of gestation in the Hospital de la Fe, reference hospital of the area, and who complied with the inclusion criteria: (1) To be at least 16 years; (2) To be in the week 10-13 of gestation; (3) to have a unique pregnancy; (4) To have the intention of continuing the follow-up and delivering in the corresponding centres of reference; (5) Not to have any impediment for the communication and (6) Not to suffer any chronic disease prior to the pregnancy.

During the pregnancy the follow-up was carried out at weeks 12 and 32. In these follow-ups, biological samples were obtained (blood, nail and urine) and also data related to diet, jobs of the progenitors and exposure to pollutants.

The newborns were followed along the childhood. A visit was made when they were 1 year, in which the neurological development, the anthropometry, the respiratory health, the diet and the environmental exposures were measured and studied. Moreover, the levels of atmospheric pollutants were measured in the homes (in and outside) of half of the children; in order to make this, dosimeters were installed for 15 days at their homes. At 2 years, a telephonic interview was made, and at 4 years they were appointed to go to the Hospital de la Fe in order to evaluate their dietary habits, their growth and to be able to obtain biological samples (urine, hair and blood) to measure nutrients and exposure to environmental pollutants.

mapavalencia

 

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325 Results

Metals -
No persistent organic compounds -


Serum metal levels in a population of Spanish pregnant women

Miren Begoña Zubero, Sabrina Llop, Amaia Irizar, Mario Murcia , Amaia Molinuevo, Ferrán Ballester , Michael Levi , Manuel Lozano , Mikel Ayerdi, Loreto Santa-Marina. Serum metal levels in a population of Spanish pregnant women. Gac Sanit. 2022-2021 Oct 6;S0213-9111(21)00159-X. Online ahead of print. PMID: 34627659


Hormonal disturbances -
Persistent organic compounds -


Maternal Perfluoroalkyl Substances, Thyroid Hormones, and DIO Genes: A Spanish Cross-sectional Study

Sarzo B, Ballesteros V, Iñiguez C, Manzano-Salgado CB, Casas M, Llop S, Murcia M, Guxens M, Vrijheid M, Marina LS, Schettgen T, Espada M, Irizar A, Fernandez-Jimenez N, Ballester F, Lopez-Espinosa MJ. Maternal Perfluoroalkyl Substances, Thyroid Hormones, and DIO Genes: A Spanish Cross-sectional Study. Environ Sci Technol. 2022-2021 Jul 27. Online ahead of print. PMID: 34314170


Neurodevelopment -
Social inequalities -


Poverty, social exclusion, and mental health: the role of the family context in children aged 7-11 years INMA mother-and-child cohort study

González L, Estarlich M, Murcia M, Barreto-Zarza F, Santa-Marina L, Simó S, Larrañaga MI, Ruiz-Palomino E, Ibarluzea J, Rebagliato M. Poverty, social exclusion, and mental health: the role of the family context in children aged 7-11 years INMA mother-and-child cohort study. Eur Child Adolesc Psychiatry. 2022-2021 Jul 26. Online ahead of print. PMID: 34312704


Entorno urbano y Verdor -
Postnatal growth and Obesity -


Green CURIOCITY: a study protocol for a European birth cohort study analysing childhood heat-related health impacts and protective effects of urban natural environments

van den Bosch M, Basagaña X, Mudu P, Kendrovski V, Maitre L, Hjertager Krog N, Aasvang GM, Grazuleviciene R, McEachan R, Vrijheid M, Nieuwenhuijsen MJ. Green CURIOCITY: a study protocol for a European birth cohort study analysing childhood heat-related health impacts and protective effects of urban natural environments. BMJ Open. 2022 Jan 24;12(1):e052537. PMID: 35074814


Air pollution -
Intrauterine growth -


Identifying Sensitive Windows of Exposure to NO2 and Fetal Growth Trajectories in a Spanish Birth Cohort

Whitworth KW, Rector A, Ish J, Chauhan SPJ, Ibarluzea J, Guxens M, Swartz MD, Symanski E, Iñiguez C. Identifying Sensitive Windows of Exposure to NO2 and Fetal Growth Trajectories in a Spanish Birth Cohort. Epidemiology. 2022 May 1;33(3):318-324. PMID: 35213509


No persistent organic compounds -
Respiratory health and atopy -


In utero exposure to bisphenols and asthma, wheeze, and lung function in school-age children: a prospective meta-analysis of 8 European birth cohorts

Abellan A, Mensink-Bout SM, Garcia-Esteban R, Beneito A, Chatzi L, Duarte-Salles T, Fernandez MF, Garcia-Aymerich J, Granum B, Iñiguez C, Jaddoe VWV, Kannan K, Lertxundi A, Lopez-Espinosa MJ, Philippat C, Sakhi AK, Santos S, Siroux V, Sunyer J, Trasande L, Vafeiadi M, Vela-Soria F, Yang TC, Zabaleta C, Vrijheid M, Duijts L, Casas M. In utero exposure to bisphenols and asthma, wheeze, and lung function in school-age children: a prospective meta-analysis of 8 European birth cohorts. Environ Int. 2022 Apr;162:107178. doi: 10.1016/j.envint.2022.107178. Epub 2022 Mar 18. PMID: 35314078.


Occupational health -
Reproductive health -


Maternal occupational exposures and fetal growth in a Spanish birth cohort

Ish J, Gimeno Ruiz de Porras D, Symanski E, Ballester F, Casas M, Delclos GL, Guxens M, Ibarluzea J, Iñiguez C, Santa-Marina L, Swartz MD, Whitworth KW. Maternal occupational exposures and fetal growth in a Spanish birth cohort. PLoS One. 2022 Apr 7;17(4):e0264530. PMID: 35390005


Neurodevelopment -
Nutrition -


Omega-3 Fatty Acid Intake during Pregnancy and Child Neuropsychological Development: A Multi-Centre Population-Based Birth Cohort Study in Spain

Tahaei H, Gignac F, Pinar A, Fernandez-Barrés S, Romaguera D, Vioque J, Santa-Marina L, Subiza-Pérez M, Llop S, Soler-Blasco R, Arija V, Salas-Salvadó J, Tardón A, Riaño-Galán I, Sunyer J, Guxens M, Julvez J. Omega-3 Fatty Acid Intake during Pregnancy and Child Neuropsychological Development: A Multi-Centre Population-Based Birth Cohort Study in Spain. Nutrients. 2022 Jan 25;14(3):518. doi: 10.3390/nu14030518. PMID: 35276877


Metals -
Neurodevelopment -
Nutrition -


Prenatal arsenic exposure, arsenic methylation efficiency, and neuropsychological development among preschool children in a Spanish birth cohort

Soler-Blasco R, Murcia M, Lozano M, Sarzo B, Esplugues A, Riutort-Mayol G, Vioque J, Lertxundi N, Santa Marina L, Lertxundi A, Irizar A, Braeuer S, Ballester F, Llop S. Prenatal arsenic exposure, arsenic methylation efficiency, and neuropsychological development among preschool children in a Spanish birth cohort. Environ Res. 2022 May 1;207:112208. PMID: 34662579


Metals -
Nutrition -
Tobacco -


Exposure to metals and metalloids among pregnant women from Spain: Levels and associated factors

Lozano M, Murcia M, Soler-Blasco R, Casas M, Zubero B, Riutort-Mayol G, Gil F, Olmedo P, Grimalt JO, Amorós R, Lertxundi A, Vrijheid M, Ballester F, Llop S. Exposure to metals and metalloids among pregnant women from Spain: Levels and associated factors. Chemosphere. 2022 Jan;286(Pt 2):131809. PMID: 34388877


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