Valencia

In October 2003 the pilot study for the creation of the INMA cohort in Valencia was carried out. In February 2004 started the recruitment of the cohort that went on until June 2005. 855 women that belonged to the departments of health 6 (34 municipalities) and 7 (two quarters of Valencia) were recruited. They were selected by consecutive sampling of among all those of the area of study that went to the population sieving of the syndrome of Down that is carried out among the 10-13 weeks of gestation in the Hospital de la Fe, reference hospital of the area, and who complied with the inclusion criteria: (1) To be at least 16 years; (2) To be in the week 10-13 of gestation; (3) to have a unique pregnancy; (4) To have the intention of continuing the follow-up and delivering in the corresponding centres of reference; (5) Not to have any impediment for the communication and (6) Not to suffer any chronic disease prior to the pregnancy.

During the pregnancy the follow-up was carried out at weeks 12 and 32. In these follow-ups, biological samples were obtained (blood, nail and urine) and also data related to diet, jobs of the progenitors and exposure to pollutants.

The newborns were followed along the childhood. A visit was made when they were 1 year, in which the neurological development, the anthropometry, the respiratory health, the diet and the environmental exposures were measured and studied. Moreover, the levels of atmospheric pollutants were measured in the homes (in and outside) of half of the children; in order to make this, dosimeters were installed for 15 days at their homes. At 2 years, a telephonic interview was made, and at 4 years they were appointed to go to the Hospital de la Fe in order to evaluate their dietary habits, their growth and to be able to obtain biological samples (urine, hair and blood) to measure nutrients and exposure to environmental pollutants.

mapavalencia

 

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367 Results

Air pollution -
Intrauterine growth -


Susceptible windows of exposure to fine particulate matter and fetal growth trajectories in the Spanish INMA (INfancia y Medio Ambiente) birth cohort

Chen WJ, Rector AM, Guxens M, Iniguez C, Swartz MD, Symanski E, Ibarluzea J, Ambros A, Estarlich M, Lertxundi A, Riano-Galán I, Sunyer J, Fernandez-Somoano A, Chauhan SP, Ish J, Whitworth KW. Susceptible windows of exposure to fine particulate matter and fetal growth trajectories in the Spanish INMA (INfancia y Medio Ambiente) birth cohort. Environ Res. 2023 Jan 1;216(Pt 2):114628. PMID: 36279916


Air pollution -
Built environment and Greeness -
Neurodevelopment -
Physical activity - sedentary lifestyle -
Postnatal growth and Obesity -
Social inequalities -


Social inequalities, green and blue spaces and mental health in 6-12 years old children participating in the INMA cohort

Subiza-Pérez M, García-Baquero G, Fernández-Somoano A, Riaño I, González L, Delgado-Saborit JM, Guxens M, Fossati S, Vrijheid M, Fernandes A, Ibarluzea J, Lertxundi N. Social inequalities, green and blue spaces and mental health in 6-12 years old children participating in the INMA cohort. Health Place. 2023 Sep;83:103104. PMID: 37611380


Air pollution -
Built environment and Greeness -
Neurodevelopment -
Physical activity - sedentary lifestyle -
Postnatal growth and Obesity -
Social inequalities -


Residential green and blue spaces and working memory in children aged 6-12 years old. Results from the INMA cohort

Subiza-Pérez M, García-Baquero G, Fernández-Somoano A, Guxens M, González L, Tardón A, Dadvand P, Estarlich M, de Castro M, McEachan RRC, Ibarluzea J, Lertxundi N. Residential green and blue spaces and working memory in children aged 6-12 years old. Results from the INMA cohort. Health Place. 2023 Nov;84:103136. PMID: 37871446


Postnatal growth and Obesity -
Reproductive health -


Associations of Maternal Educational Level, Proximity to Greenspace During Pregnancy, and Gestational Diabetes With Body Mass Index From Infancy to Early Adulthood: A Proof-of-Concept Federated Analysis in 18 Birth Cohorts

Cadman T, Elhakeem A, Vinther JL, Avraam D, Carrasco P, Calas L, Cardo M, Charles MA, Corpeleijn E, Crozier S, de Castro M, Estarlich M, Fernandes A, Fossatti S, Gruszfeld D, Gurlich K, Grote V, Haakma S, Harris JR, Heude B, Huang RC, Ibarluzea J, Inskip H, Jaddoe V, Koletzko B, Luque V, Manios Y, Moirano G, Moschonis G, Nader J, Nieuwenhuijsen M, Andersen AN, McEachen R, de Moira AP, Popovic M, Roumeliotaki T, Salika T, Marina LS, Santos S, Serbert S, Tzorovili E, Vafeiadi M, Verduci E, Vrijheid M, Vrijkotte TGM, Welten M, Wright J, Yang TC, Zugna D, Lawlor D. Associations of Maternal Educational Level, Proximity to Greenspace During Pregnancy, and Gestational Diabetes With Body Mass Index From Infancy to Early Adulthood: A Proof-of-Concept Federated Analysis in 18 Birth Cohorts. Am J Epidemiol. 2024-2023 Oct 19:kwad206. doi: 10.1093/aje/kwad206. Epub ahead of print. PMID: 37856700


No persistent organic compounds -


Associated factors with mycotoxin exposure in Spanish population

Dasí-Navarro N, Lozano M, Llop S, Vioque J, Peiro J, Esplugues A, Manyes L, Vila-Donat P. Associated factors with mycotoxin exposure in Spanish population. Environ Res. 2024 Feb 1;242:117618. PMID: 37967699


Exposome -
Vitamin D -


Sociodemographic, lifestyle, and environmental determinants of vitamin D levels in pregnant women in Spain

Llopis M, Ventura PS, Brachowicz N, Sangüesa J, Murcia M, Lopez-Espinosa MJ, García-Baquero G, Lertxundi A, Vrijheid M, Casas M, Petrone P. Sociodemographic, lifestyle, and environmental determinants of vitamin D levels in pregnant women in Spain. Environ Int. 2023 Dec;182:108293. PMID: 37984291


Neurodevelopment -
Sleep problems -


Sleep problems at ages 8-9 and ADHD symptoms at ages 10-11: evidence in three cohorts from INMA study

González-Safont L, Rebagliato M, Arregi A, Carrasco P, Guxens M, Vegas O, Julvez J, Estarlich M. Sleep problems at ages 8-9 and ADHD symptoms at ages 10-11: evidence in three cohorts from INMA study. Eur J Pediatr. 2023 Nov;182(11):5211-5222. PMID: 37721582


No persistent organic compounds -
Persistent organic compounds -
Postnatal growth and Obesity -


Prenatal Exposure to Multiple Endocrine-Disrupting Chemicals and Childhood BMI Trajectories in the INMA Cohort Study

Montazeri P, Güil-Oumrait N, Marquez S, Cirugeda L, Beneito A, Guxens M, Lertxundi A, Lopez-Espinosa MJ, Santa-Marina L, Sunyer J, Casas M, Vrijheid M. Prenatal Exposure to Multiple Endocrine-Disrupting Chemicals and Childhood BMI Trajectories in the INMA Cohort Study. Environ Health Perspect. 2023 Oct;131(10):107006. PMID: 37850789


Epigenetics -
Nutrition -


Folic Acid Supplementation during Pregnancy and Its Association with Telomere Length in Children at Four Years: Results from the INMA Birth Cohort Study

Petermann-Rocha F, Valera-Gran D, Prieto-Botella D, Martens DS, Gonzalez-Palacios S, Riaño-Galán I, Murcia M, Irizar A, Julvez J, Santa-Marina L, Tardón A, Sunyer J, Vioque J, Nawrot T, Navarrete-Muñoz EM. Folic Acid Supplementation during Pregnancy and Its Association with Telomere Length in Children at Four Years: Results from the INMA Birth Cohort Study. Nutrients. 2023 Oct 9;15(19):4303. PMID: 37836587


Postnatal growth and Obesity -


Lifestyle patterns in European preschoolers: Associations with socio-demographic factors and body mass index

Descarpentrie A, Calas L, Cornet M, Heude B, Charles MA, Avraam D, Brescianini S, Cadman T, Elhakeem A, Fernández-Barrés S, Harris JR, Inskip H, Julvez J, Llop S, Margetaki K, Maritano S, Nader JLT, Roumeliotaki T, Salika T, Subiza-Pérez M, Vafeiadi M, Vrijheid M, Wright J, Yang T, Dargent-Molina P, Lioret S. Lifestyle patterns in European preschoolers: Associations with socio-demographic factors and body mass index. Pediatr Obes. 2023 Dec;18(12):e13079. PMID: 37795656


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